PhosphoNET

           
Protein Info 
   
Short Name:  KRT16
Full Name:  Keratin, type I cytoskeletal 16
Alias:  CK16; CK-16; Cytokeratin-16; Focal non-epidermolytic palmoplantar keratoderma; K1C16; K1CP; Keratin 16; Keratin-16; KRT16A; NEPPK
Type:  Cytoskeletal protein
Mass (Da):  51268
Number AA:  473
UniProt ID:  P08779
International Prot ID:  IPI00217963
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005882     Uniprot OncoNet
Molecular Function:  GO:0005515  GO:0005200   PhosphoSite+ KinaseNET
Biological Process:  GO:0008283  GO:0008544   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T9TTCSRQFTSSSSMKG
Site 2S10TCSRQFTSSSSMKGS
Site 3S11CSRQFTSSSSMKGSC
Site 4S12SRQFTSSSSMKGSCG
Site 5S13RQFTSSSSMKGSCGI
Site 6S17SSSSMKGSCGIGGGI
Site 7S28GGGIGGGSSRISSVL
Site 8S32GGGSSRISSVLAGGS
Site 9S33GGSSRISSVLAGGSC
Site 10S39SSVLAGGSCRAPSTY
Site 11S44GGSCRAPSTYGGGLS
Site 12T45GSCRAPSTYGGGLSV
Site 13Y46SCRAPSTYGGGLSVS
Site 14S51STYGGGLSVSSRFSS
Site 15S53YGGGLSVSSRFSSGG
Site 16S54GGGLSVSSRFSSGGA
Site 17S73GGYGGGFSSSSSFGS
Site 18S74GYGGGFSSSSSFGSG
Site 19S75YGGGFSSSSSFGSGF
Site 20S76GGGFSSSSSFGSGFG
Site 21S77GGFSSSSSFGSGFGG
Site 22S80SSSSSFGSGFGGGYG
Site 23S116GDGLLVGSEKVTMQN
Site 24T120LVGSEKVTMQNLNDR
Site 25S130NLNDRLASYLDKVRA
Site 26Y131LNDRLASYLDKVRAL
Site 27Y153EVKIRDWYQRQRPSE
Site 28S159WYQRQRPSEIKDYSP
Site 29Y164RPSEIKDYSPYFKTI
Site 30S165PSEIKDYSPYFKTIE
Site 31Y167EIKDYSPYFKTIEDL
Site 32Y206ADDFRTKYEHELALR
Site 33T215HELALRQTVEADVNG
Site 34T231RRVLDELTLARTDLE
Site 35T235DELTLARTDLEMQIE
Site 36Y250GLKEELAYLRKNHEE
Site 37T266MLALRGQTGGDVNVE
Site 38S283AAPGVDLSRILNEMR
Site 39Y293LNEMRDQYEQMAEKN
Site 40T306KNRRDAETWFLSKTE
Site 41S310DAETWFLSKTEELNK
Site 42T312ETWFLSKTEELNKEV
Site 43S321ELNKEVASNSELVQS
Site 44S323NKEVASNSELVQSSR
Site 45S328SNSELVQSSRSEVTE
Site 46S329NSELVQSSRSEVTEL
Site 47S331ELVQSSRSEVTELRR
Site 48S349GLEIELQSQLSMKAS
Site 49S352IELQSQLSMKASLEN
Site 50S356SQLSMKASLENSLEE
Site 51S360MKASLENSLEETKGR
Site 52T364LENSLEETKGRYCMQ
Site 53S381QIQGLIGSVEEQLAQ
Site 54S397RCEMEQQSQEYQILL
Site 55T408QILLDVKTRLEQEIA
Site 56T416RLEQEIATYRRLLEG
Site 57Y417LEQEIATYRRLLEGE
Site 58S429EGEDAHLSSQQASGQ
Site 59S430GEDAHLSSQQASGQS
Site 60S434HLSSQQASGQSYSSR
Site 61S437SQQASGQSYSSREVF
Site 62Y438QQASGQSYSSREVFT
Site 63S439QASGQSYSSREVFTS
Site 64S440ASGQSYSSREVFTSS
Site 65T445YSSREVFTSSSSSSS
Site 66S446SSREVFTSSSSSSSR
Site 67S447SREVFTSSSSSSSRQ
Site 68S448REVFTSSSSSSSRQT
Site 69S449EVFTSSSSSSSRQTR
Site 70S450VFTSSSSSSSRQTRP
Site 71S451FTSSSSSSSRQTRPI
Site 72S452TSSSSSSSRQTRPIL
Site 73T455SSSSSRQTRPILKEQ
Site 74S463RPILKEQSSSSFSQG
Site 75S464PILKEQSSSSFSQGQ
Site 76S465ILKEQSSSSFSQGQS
Site 77S466LKEQSSSSFSQGQSS
Site 78S468EQSSSSFSQGQSS__
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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