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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HOXC4
Full Name:
Homeobox protein Hox-C4
Alias:
Homeobox protein CP19;Homeobox protein Hox-3E
Type:
Mass (Da):
29811
Number AA:
264
UniProt ID:
P09017
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y12
S
Y
L
M
D
S
N
Y
I
D
P
K
F
P
P
Site 2
Y23
K
F
P
P
C
E
E
Y
S
Q
N
S
Y
I
P
Site 3
S24
F
P
P
C
E
E
Y
S
Q
N
S
Y
I
P
E
Site 4
S27
C
E
E
Y
S
Q
N
S
Y
I
P
E
H
S
P
Site 5
Y28
E
E
Y
S
Q
N
S
Y
I
P
E
H
S
P
E
Site 6
S33
N
S
Y
I
P
E
H
S
P
E
Y
Y
G
R
T
Site 7
Y36
I
P
E
H
S
P
E
Y
Y
G
R
T
R
E
S
Site 8
Y37
P
E
H
S
P
E
Y
Y
G
R
T
R
E
S
G
Site 9
Y53
Q
H
H
H
Q
E
L
Y
P
P
P
P
P
R
P
Site 10
S61
P
P
P
P
P
R
P
S
Y
P
E
R
Q
Y
S
Site 11
Y62
P
P
P
P
R
P
S
Y
P
E
R
Q
Y
S
C
Site 12
Y67
P
S
Y
P
E
R
Q
Y
S
C
T
S
L
Q
G
Site 13
S68
S
Y
P
E
R
Q
Y
S
C
T
S
L
Q
G
P
Site 14
T70
P
E
R
Q
Y
S
C
T
S
L
Q
G
P
G
N
Site 15
S71
E
R
Q
Y
S
C
T
S
L
Q
G
P
G
N
S
Site 16
S78
S
L
Q
G
P
G
N
S
R
G
H
G
P
A
Q
Site 17
S94
G
H
H
H
P
E
K
S
Q
S
L
C
E
P
A
Site 18
S96
H
H
P
E
K
S
Q
S
L
C
E
P
A
P
L
Site 19
S104
L
C
E
P
A
P
L
S
G
A
S
A
S
P
S
Site 20
S107
P
A
P
L
S
G
A
S
A
S
P
S
P
A
P
Site 21
S109
P
L
S
G
A
S
A
S
P
S
P
A
P
P
A
Site 22
S111
S
G
A
S
A
S
P
S
P
A
P
P
A
C
S
Site 23
S118
S
P
A
P
P
A
C
S
Q
P
A
P
D
H
P
Site 24
S126
Q
P
A
P
D
H
P
S
S
A
A
S
K
Q
P
Site 25
S127
P
A
P
D
H
P
S
S
A
A
S
K
Q
P
I
Site 26
S130
D
H
P
S
S
A
A
S
K
Q
P
I
V
Y
P
Site 27
Y136
A
S
K
Q
P
I
V
Y
P
W
M
K
K
I
H
Site 28
T146
M
K
K
I
H
V
S
T
V
N
P
N
Y
N
G
Site 29
Y151
V
S
T
V
N
P
N
Y
N
G
G
E
P
K
R
Site 30
S159
N
G
G
E
P
K
R
S
R
A
A
Y
T
R
Q
Site 31
Y163
P
K
R
S
R
A
A
Y
T
R
Q
Q
V
L
E
Site 32
Y177
E
L
E
K
E
F
H
Y
N
R
Y
L
T
R
R
Site 33
Y180
K
E
F
H
Y
N
R
Y
L
T
R
R
R
R
I
Site 34
T182
F
H
Y
N
R
Y
L
T
R
R
R
R
I
E
I
Site 35
S192
R
R
I
E
I
A
H
S
L
C
L
S
E
R
Q
Site 36
T220
K
D
H
R
L
P
N
T
K
V
R
S
A
P
P
Site 37
S224
L
P
N
T
K
V
R
S
A
P
P
A
G
A
A
Site 38
S236
G
A
A
P
S
T
L
S
A
A
T
P
G
T
S
Site 39
T239
P
S
T
L
S
A
A
T
P
G
T
S
E
D
H
Site 40
S243
S
A
A
T
P
G
T
S
E
D
H
S
Q
S
A
Site 41
S247
P
G
T
S
E
D
H
S
Q
S
A
T
P
P
E
Site 42
S249
T
S
E
D
H
S
Q
S
A
T
P
P
E
Q
Q
Site 43
T251
E
D
H
S
Q
S
A
T
P
P
E
Q
Q
R
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation