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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FBPase
Full Name:
Fructose-1,6-bisphosphatase 1
Alias:
D-fructose-1,6-bisphosphate 1-phosphohydrolase; EC 3.1.3.11; F16P; F16P1; FBP; FBP1
Type:
Enzyme
Mass (Da):
36814
Number AA:
337
UniProt ID:
P09467
International Prot ID:
IPI00073772
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0042132
GO:0004331
GO:0042802
PhosphoSite+
KinaseNET
Biological Process:
GO:0006094
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
A
D
Q
A
P
F
D
T
D
V
N
T
L
T
R
Site 2
T13
P
F
D
T
D
V
N
T
L
T
R
F
V
M
E
Site 3
T28
E
G
R
K
A
R
G
T
G
E
L
T
Q
L
L
Site 4
Y58
K
A
G
I
A
H
L
Y
G
I
A
G
S
T
N
Site 5
S63
H
L
Y
G
I
A
G
S
T
N
V
T
G
D
Q
Site 6
Y114
E
P
E
K
R
G
K
Y
V
V
C
F
D
P
L
Site 7
T135
D
C
L
V
S
V
G
T
I
F
G
I
Y
R
K
Site 8
Y140
V
G
T
I
F
G
I
Y
R
K
K
S
T
D
E
Site 9
S144
F
G
I
Y
R
K
K
S
T
D
E
P
S
E
K
Site 10
T145
G
I
Y
R
K
K
S
T
D
E
P
S
E
K
D
Site 11
S149
K
K
S
T
D
E
P
S
E
K
D
A
L
Q
P
Site 12
Y210
I
K
K
K
G
K
I
Y
S
L
N
E
G
Y
A
Site 13
S211
K
K
K
G
K
I
Y
S
L
N
E
G
Y
A
K
Site 14
Y216
I
Y
S
L
N
E
G
Y
A
K
D
F
D
P
A
Site 15
S238
K
K
F
P
P
D
N
S
A
P
Y
G
A
R
Y
Site 16
Y241
P
P
D
N
S
A
P
Y
G
A
R
Y
V
G
S
Site 17
Y245
S
A
P
Y
G
A
R
Y
V
G
S
M
V
A
D
Site 18
S248
Y
G
A
R
Y
V
G
S
M
V
A
D
V
H
R
Site 19
T256
M
V
A
D
V
H
R
T
L
V
Y
G
G
I
F
Site 20
Y259
D
V
H
R
T
L
V
Y
G
G
I
F
L
Y
P
Site 21
Y265
V
Y
G
G
I
F
L
Y
P
A
N
K
K
S
P
Site 22
S271
L
Y
P
A
N
K
K
S
P
N
G
K
L
R
L
Site 23
Y280
N
G
K
L
R
L
L
Y
E
C
N
P
M
A
Y
Site 24
Y287
Y
E
C
N
P
M
A
Y
V
M
E
K
A
G
G
Site 25
Y332
V
L
E
F
L
K
V
Y
E
K
H
S
A
Q
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation