PhosphoNET

           
Protein Info 
   
Short Name:  WNT2
Full Name:  Protein Wnt-2
Alias:  Int-1-like protein 1;Int-1-related protein
Type: 
Mass (Da):  40418
Number AA:  360
UniProt ID:  P09544
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y29EVNSSWWYMRATGGS
Site 2S50NVPGLVSSQRQLCHR
Site 3S66PDVMRAISQGVAEWT
Site 4S95NTLDRDHSLFGRVLL
Site 5S105GRVLLRSSRESAFVY
Site 6S115SAFVYAISSAGVVFA
Site 7T124AGVVFAITRACSQGE
Site 8S128FAITRACSQGEVKSC
Site 9S134CSQGEVKSCSCDPKK
Site 10S136QGEVKSCSCDPKKMG
Site 11S144CDPKKMGSAKDSKGI
Site 12S148KMGSAKDSKGIFDWG
Site 13Y163GCSDNIDYGIKFARA
Site 14T230AMADFRKTGDYLWRK
Site 15Y233DFRKTGDYLWRKYNG
Site 16Y238GDYLWRKYNGAIQVV
Site 17T254NQDGTGFTVANERFK
Site 18T264NERFKKPTKNDLVYF
Site 19Y270PTKNDLVYFENSPDY
Site 20Y277YFENSPDYCIRDREA
Site 21S286IRDREAGSLGTAGRV
Site 22T297AGRVCNLTSRGMDSC
Site 23Y313VMCCGRGYDTSHVTR
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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