PhosphoNET

           
Protein Info 
   
Short Name:  CSF1
Full Name:  Macrophage colony-stimulating factor 1
Alias:  CSF-1; Lanimostim; Macrophage colony-stimulating factor 1; MCSF; M-CSF
Type:  Cytokine
Mass (Da):  60119
Number AA:  554
UniProt ID:  P09603
International Prot ID:  IPI00015881
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005615  GO:0016021  GO:0048471 Uniprot OncoNet
Molecular Function:  GO:0005125  GO:0008083  GO:0005157 PhosphoSite+ KinaseNET
Biological Process:  GO:0008283  GO:0030225  GO:0042117 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S30VCLLASRSITEEVSE
Site 2T32LLASRSITEEVSEYC
Site 3Y38ITEEVSEYCSHMIGS
Site 4S50IGSGHLQSLQRLIDS
Site 5S57SLQRLIDSQMETSCQ
Site 6T61LIDSQMETSCQITFE
Site 7T66METSCQITFEFVDQE
Site 8T103TMRFRDNTPNAIAIV
Site 9S121ELSLRLKSCFTKDYE
Site 10Y127KSCFTKDYEEHDKAC
Site 11T137HDKACVRTFYETPLQ
Site 12T141CVRTFYETPLQLLEK
Site 13S174FSKNCNNSFAECSSQ
Site 14S180NSFAECSSQDVVTKP
Site 15Y193KPDCNCLYPKAIPSS
Site 16S199LYPKAIPSSDPASVS
Site 17S200YPKAIPSSDPASVSP
Site 18S204IPSSDPASVSPHQPL
Site 19S206SSDPASVSPHQPLAP
Site 20T222MAPVAGLTWEDSEGT
Site 21S226AGLTWEDSEGTEGSS
Site 22S233SEGTEGSSLLPGEQP
Site 23T243PGEQPLHTVDPGSAK
Site 24S248LHTVDPGSAKQRPPR
Site 25S256AKQRPPRSTCQSFEP
Site 26T257KQRPPRSTCQSFEPP
Site 27S260PPRSTCQSFEPPETP
Site 28T266QSFEPPETPVVKDST
Site 29S272ETPVVKDSTIGGSPQ
Site 30T273TPVVKDSTIGGSPQP
Site 31S277KDSTIGGSPQPRPSV
Site 32S283GSPQPRPSVGAFNPG
Site 33T301ILDSAMGTNWVPEEA
Site 34S313EEASGEASEIPVPQG
Site 35S324VPQGTELSPSRPGGG
Site 36S326QGTELSPSRPGGGSM
Site 37S332PSRPGGGSMQTEPAR
Site 38T335PGGGSMQTEPARPSN
Site 39S341QTEPARPSNFLSASS
Site 40S345ARPSNFLSASSPLPA
Site 41S347PSNFLSASSPLPASA
Site 42S348SNFLSASSPLPASAK
Site 43S353ASSPLPASAKGQQPA
Site 44T363GQQPADVTGTALPRV
Site 45T376RVGPVRPTGQDWNHT
Site 46T383TGQDWNHTPQKTDHP
Site 47T387WNHTPQKTDHPSALL
Site 48S402RDPPEPGSPRISSLR
Site 49S406EPGSPRISSLRPQGL
Site 50S407PGSPRISSLRPQGLS
Site 51S414SLRPQGLSNPSTLSA
Site 52T418QGLSNPSTLSAQPQL
Site 53S420LSNPSTLSAQPQLSR
Site 54S426LSAQPQLSRSHSSGS
Site 55S428AQPQLSRSHSSGSVL
Site 56S430PQLSRSHSSGSVLPL
Site 57S431QLSRSHSSGSVLPLG
Site 58S433SRSHSSGSVLPLGEL
Site 59S445GELEGRRSTRDRRSP
Site 60T446ELEGRRSTRDRRSPA
Site 61S451RSTRDRRSPAEPEGG
Site 62S461EPEGGPASEGAARPL
Site 63S473RPLPRFNSVPLTDTG
Site 64T477RFNSVPLTDTGHERQ
Site 65S485DTGHERQSEGSSSPQ
Site 66S488HERQSEGSSSPQLQE
Site 67S489ERQSEGSSSPQLQES
Site 68S490RQSEGSSSPQLQESV
Site 69Y518AVGGLLFYRWRRRSH
Site 70S524FYRWRRRSHQEPQRA
Site 71S533QEPQRADSPLEQPEG
Site 72S541PLEQPEGSPLTQDDR
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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