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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DLD
Full Name:
Dihydrolipoyl dehydrogenase, mitochondrial
Alias:
Dihydrolipoamide dehydrogenase
Type:
Mass (Da):
54132
Number AA:
509
UniProt ID:
P09622
International Prot ID:
IPI00015911
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005739
GO:0005759
Uniprot
OncoNet
Molecular Function:
GO:0000166
GO:0003824
GO:0004148
PhosphoSite+
KinaseNET
Biological Process:
GO:0008152
GO:0009987
GO:0019725
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y8
M
Q
S
W
S
R
V
Y
C
S
L
A
K
R
G
Site 2
S21
R
G
H
F
N
R
I
S
H
G
L
Q
G
L
S
Site 3
S28
S
H
G
L
Q
G
L
S
A
V
P
L
R
T
Y
Site 4
T34
L
S
A
V
P
L
R
T
Y
A
D
Q
P
I
D
Site 5
Y35
S
A
V
P
L
R
T
Y
A
D
Q
P
I
D
A
Site 6
T67
A
A
Q
L
G
F
K
T
V
C
I
E
K
N
E
Site 7
Y97
A
L
L
N
N
S
H
Y
Y
H
M
A
H
G
T
Site 8
Y98
L
L
N
N
S
H
Y
Y
H
M
A
H
G
T
D
Site 9
S114
A
S
R
G
I
E
M
S
E
V
R
L
N
L
D
Site 10
S128
D
K
M
M
E
Q
K
S
T
A
V
K
A
L
T
Site 11
T129
K
M
M
E
Q
K
S
T
A
V
K
A
L
T
G
Site 12
Y153
K
V
V
H
V
N
G
Y
G
K
I
T
G
K
N
Site 13
T204
E
D
T
I
V
S
S
T
G
A
L
S
L
K
K
Site 14
S208
V
S
S
T
G
A
L
S
L
K
K
V
P
E
K
Site 15
S230
V
I
G
V
E
L
G
S
V
W
Q
R
L
G
A
Site 16
T276
G
F
K
F
K
L
N
T
K
V
T
G
A
T
K
Site 17
S285
V
T
G
A
T
K
K
S
D
G
K
I
D
V
S
Site 18
S292
S
D
G
K
I
D
V
S
I
E
A
A
S
G
G
Site 19
S297
D
V
S
I
E
A
A
S
G
G
K
A
E
V
I
Site 20
T319
C
I
G
R
R
P
F
T
K
N
L
G
L
E
E
Site 21
T341
R
G
R
I
P
V
N
T
R
F
Q
T
K
I
P
Site 22
T345
P
V
N
T
R
F
Q
T
K
I
P
N
I
Y
A
Site 23
Y416
L
K
E
E
G
I
E
Y
K
V
G
K
F
P
F
Site 24
S427
K
F
P
F
A
A
N
S
R
A
K
T
N
A
D
Site 25
T431
A
A
N
S
R
A
K
T
N
A
D
T
D
G
M
Site 26
S446
V
K
I
L
G
Q
K
S
T
D
R
V
L
G
A
Site 27
T447
K
I
L
G
Q
K
S
T
D
R
V
L
G
A
H
Site 28
S491
C
H
A
H
P
T
L
S
E
A
F
R
E
A
N
Site 29
S502
R
E
A
N
L
A
A
S
F
G
K
S
I
N
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation