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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
IFIT2
Full Name:
Interferon-induced protein with tetratricopeptide repeats 2
Alias:
Cig42; G10P2; GARG-39; IFI54; IFI-54; IFI-54K; IFIT-2; Interferon, alpha-inducible protein (MW 54kD); Interferon-induced 54; Interferon-induced 54 kDa; Interferon-induced, with tetratricopeptide repeats 2; ISG-54 K; ISG-54K
Type:
Intracellular membrane-bound organelle protein
Mass (Da):
54632
Number AA:
472
UniProt ID:
P09913
International Prot ID:
IPI00018298
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0043231
Uniprot
OncoNet
Molecular Function:
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S2
_
_
_
_
_
_
M
S
E
N
N
K
N
S
L
Site 2
S8
M
S
E
N
N
K
N
S
L
E
S
S
L
R
Q
Site 3
S12
N
K
N
S
L
E
S
S
L
R
Q
L
K
C
H
Site 4
S30
N
L
M
E
G
E
N
S
L
D
D
F
E
D
K
Site 5
Y105
G
N
Y
A
W
V
Y
Y
H
M
G
R
L
S
D
Site 6
Y116
R
L
S
D
V
Q
I
Y
V
D
K
V
K
H
V
Site 7
S129
H
V
C
E
K
F
S
S
P
Y
R
I
E
S
P
Site 8
S135
S
S
P
Y
R
I
E
S
P
E
L
D
C
E
E
Site 9
S182
T
S
G
L
A
I
A
S
Y
R
L
D
N
W
P
Site 10
Y183
S
G
L
A
I
A
S
Y
R
L
D
N
W
P
P
Site 11
S191
R
L
D
N
W
P
P
S
Q
N
A
I
D
P
L
Site 12
Y210
R
L
N
P
D
N
Q
Y
L
K
V
L
L
A
L
Site 13
Y307
N
L
R
E
N
G
M
Y
G
K
R
K
L
L
E
Site 14
Y350
L
H
A
L
A
D
Q
Y
E
D
A
E
Y
Y
F
Site 15
Y355
D
Q
Y
E
D
A
E
Y
Y
F
Q
K
E
F
S
Site 16
Y356
Q
Y
E
D
A
E
Y
Y
F
Q
K
E
F
S
K
Site 17
T366
K
E
F
S
K
E
L
T
P
V
A
K
Q
L
L
Site 18
Y377
K
Q
L
L
H
L
R
Y
G
N
F
Q
L
Y
Q
Site 19
Y383
R
Y
G
N
F
Q
L
Y
Q
M
K
C
E
D
K
Site 20
S405
G
V
K
I
N
Q
K
S
R
E
K
E
K
M
K
Site 21
S424
K
I
A
K
M
R
L
S
K
N
G
A
D
S
E
Site 22
S453
M
Q
Q
A
D
E
D
S
E
R
G
L
E
S
G
Site 23
S459
D
S
E
R
G
L
E
S
G
S
L
I
P
S
A
Site 24
S461
E
R
G
L
E
S
G
S
L
I
P
S
A
S
S
Site 25
S465
E
S
G
S
L
I
P
S
A
S
S
W
N
G
E
Site 26
S467
G
S
L
I
P
S
A
S
S
W
N
G
E
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation