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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
IFIT1
Full Name:
Interferon-induced protein with tetratricopeptide repeats 1
Alias:
G10p1; Garg-16; Ifi56; Ifi-56; Ifit1; Ifnai1; Interferon-induced 56 kDa protein; Interferon-induced protein with tetratricopeptide repeats 1 isoform 2; Isg56; Rnm561
Type:
Uncharacterized cytoplasm protein
Mass (Da):
55360
Number AA:
478
UniProt ID:
P09914
International Prot ID:
IPI00018300
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0044424
GO:0044464
Uniprot
OncoNet
Molecular Function:
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
D
D
H
Q
V
K
D
S
L
E
Q
L
R
C
H
Site 2
T48
D
Q
I
E
F
L
D
T
K
Y
S
V
G
I
H
Site 3
Y60
G
I
H
N
L
L
A
Y
V
K
H
L
K
G
Q
Site 4
S74
Q
N
E
E
A
L
K
S
L
K
E
A
E
N
L
Site 5
Y117
R
L
A
E
A
Q
T
Y
L
D
K
V
E
N
I
Site 6
Y157
L
K
C
G
G
K
N
Y
E
R
A
K
A
C
F
Site 7
S177
V
D
P
E
N
P
E
S
S
A
G
Y
A
I
S
Site 8
S184
S
S
A
G
Y
A
I
S
A
Y
R
L
D
G
F
Site 9
T195
L
D
G
F
K
L
A
T
K
N
H
K
P
F
S
Site 10
S202
T
K
N
H
K
P
F
S
L
L
P
L
R
Q
A
Site 11
Y218
R
L
N
P
D
N
G
Y
I
K
V
L
L
A
L
Site 12
Y239
Q
E
A
E
G
E
K
Y
I
E
E
A
L
A
N
Site 13
S249
E
A
L
A
N
M
S
S
Q
T
Y
V
F
R
Y
Site 14
Y252
A
N
M
S
S
Q
T
Y
V
F
R
Y
A
A
K
Site 15
Y256
S
Q
T
Y
V
F
R
Y
A
A
K
F
Y
R
R
Site 16
Y261
F
R
Y
A
A
K
F
Y
R
R
K
G
S
V
D
Site 17
S266
K
F
Y
R
R
K
G
S
V
D
K
A
L
E
L
Site 18
T281
L
K
K
A
L
Q
E
T
P
T
S
V
L
L
H
Site 19
S284
A
L
Q
E
T
P
T
S
V
L
L
H
H
Q
I
Site 20
Y295
H
H
Q
I
G
L
C
Y
K
A
Q
M
I
Q
I
Site 21
T338
S
A
V
E
K
K
P
T
F
E
V
A
H
L
D
Site 22
Y350
H
L
D
L
A
R
M
Y
I
E
A
G
N
H
R
Site 23
S412
A
I
K
I
E
Q
A
S
L
T
R
D
K
S
I
Site 24
T414
K
I
E
Q
A
S
L
T
R
D
K
S
I
N
S
Site 25
S418
A
S
L
T
R
D
K
S
I
N
S
L
K
K
L
Site 26
Y459
N
M
N
E
A
L
E
Y
Y
E
R
A
L
R
L
Site 27
Y460
M
N
E
A
L
E
Y
Y
E
R
A
L
R
L
A
Site 28
S473
L
A
A
D
F
E
N
S
V
R
Q
G
P
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation