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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FAM153B
Full Name:
Protein FAM153B
Alias:
Type:
Mass (Da):
43591
Number AA:
387
UniProt ID:
P0C7A2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y20
C
G
E
D
E
I
V
Y
P
R
M
P
G
E
S
Site 2
S27
Y
P
R
M
P
G
E
S
T
V
C
H
R
E
R
Site 3
T28
P
R
M
P
G
E
S
T
V
C
H
R
E
R
E
Site 4
T39
R
E
R
E
K
P
I
T
Y
H
W
Y
H
W
H
Site 5
Y43
K
P
I
T
Y
H
W
Y
H
W
H
P
G
H
I
Site 6
Y51
H
W
H
P
G
H
I
Y
P
R
V
A
S
M
E
Site 7
S56
H
I
Y
P
R
V
A
S
M
E
D
Y
D
E
D
Site 8
Y60
R
V
A
S
M
E
D
Y
D
E
D
L
V
Q
E
Site 9
S69
E
D
L
V
Q
E
A
S
S
E
D
V
L
G
V
Site 10
T83
V
H
M
V
D
K
D
T
E
R
D
I
E
M
K
Site 11
Y102
R
L
R
E
L
H
L
Y
S
T
W
K
K
Y
Q
Site 12
Y108
L
Y
S
T
W
K
K
Y
Q
E
A
M
K
T
S
Site 13
T114
K
Y
Q
E
A
M
K
T
S
L
G
V
P
Q
C
Site 14
S127
Q
C
E
R
D
E
G
S
L
G
K
P
L
C
P
Site 15
T141
P
P
E
I
L
S
E
T
L
P
G
S
V
K
K
Site 16
S145
L
S
E
T
L
P
G
S
V
K
K
R
V
C
F
Site 17
S154
K
K
R
V
C
F
P
S
E
D
H
L
E
E
F
Site 18
S170
A
E
H
L
P
E
A
S
N
Q
S
L
L
T
V
Site 19
T176
A
S
N
Q
S
L
L
T
V
A
H
A
D
T
G
Site 20
S203
H
G
P
G
Q
T
V
S
E
E
A
T
E
V
H
Site 21
T207
Q
T
V
S
E
E
A
T
E
V
H
M
M
E
G
Site 22
T218
M
M
E
G
D
P
D
T
L
A
E
L
L
I
R
Site 23
S233
D
V
L
Q
E
L
S
S
Y
N
G
E
E
E
D
Site 24
Y234
V
L
Q
E
L
S
S
Y
N
G
E
E
E
D
P
Site 25
T246
E
D
P
E
E
V
K
T
S
L
G
V
P
Q
R
Site 26
S247
D
P
E
E
V
K
T
S
L
G
V
P
Q
R
G
Site 27
S269
H
V
P
G
Q
T
V
S
E
E
A
T
G
V
H
Site 28
T284
M
M
Q
V
D
P
A
T
P
A
K
S
D
L
E
Site 29
S288
D
P
A
T
P
A
K
S
D
L
E
D
L
E
E
Site 30
T318
M
M
Q
V
D
P
A
T
L
A
K
Q
L
E
D
Site 31
S326
L
A
K
Q
L
E
D
S
T
I
T
G
S
H
Q
Site 32
T327
A
K
Q
L
E
D
S
T
I
T
G
S
H
Q
Q
Site 33
S331
E
D
S
T
I
T
G
S
H
Q
Q
M
S
A
S
Site 34
S336
T
G
S
H
Q
Q
M
S
A
S
P
S
S
A
P
Site 35
S338
S
H
Q
Q
M
S
A
S
P
S
S
A
P
A
E
Site 36
S340
Q
Q
M
S
A
S
P
S
S
A
P
A
E
E
A
Site 37
T359
K
V
E
E
E
V
K
T
R
K
P
K
K
K
T
Site 38
T366
T
R
K
P
K
K
K
T
R
K
P
S
K
K
S
Site 39
S370
K
K
K
T
R
K
P
S
K
K
S
R
W
N
V
Site 40
S373
T
R
K
P
S
K
K
S
R
W
N
V
L
K
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation