KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ACSM4
Full Name:
Acyl-coenzyme A synthetase ACSM4, mitochondrial
Alias:
acsm4; acyl-coa synthetase medium-chain family member 4; similar to olfactory specific medium-chain acyl CoA synthetase
Type:
Mitochondrial; Ligase; EC 6.2.1.2; Carbohydrate Metabolism - butanoate
Mass (Da):
65700
Number AA:
UniProt ID:
P0C7M7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005759
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0047760
GO:0000287
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T16
T
F
R
F
I
W
L
T
K
P
P
G
R
R
L
Site 2
T31
H
K
D
H
Q
L
W
T
P
L
T
L
A
D
F
Site 3
S63
A
D
V
L
D
Q
W
S
Q
K
E
K
T
G
E
Site 4
S90
K
G
D
E
V
K
W
S
F
R
E
L
G
S
L
Site 5
S96
W
S
F
R
E
L
G
S
L
S
R
K
A
A
N
Site 6
S98
F
R
E
L
G
S
L
S
R
K
A
A
N
V
L
Site 7
T106
R
K
A
A
N
V
L
T
K
P
C
G
L
Q
R
Site 8
T149
M
P
G
T
I
Q
L
T
A
K
D
I
L
Y
R
Site 9
Y155
L
T
A
K
D
I
L
Y
R
L
R
A
S
K
A
Site 10
S177
E
V
A
P
A
V
E
S
I
V
L
E
C
P
D
Site 11
T187
L
E
C
P
D
L
K
T
K
L
L
V
S
P
Q
Site 12
S192
L
K
T
K
L
L
V
S
P
Q
S
W
N
G
W
Site 13
S195
K
L
L
V
S
P
Q
S
W
N
G
W
L
S
F
Site 14
S210
Q
E
L
F
Q
F
A
S
E
E
H
S
C
V
E
Site 15
S214
Q
F
A
S
E
E
H
S
C
V
E
T
G
S
Q
Site 16
T218
E
E
H
S
C
V
E
T
G
S
Q
E
P
M
T
Site 17
S220
H
S
C
V
E
T
G
S
Q
E
P
M
T
I
Y
Site 18
T225
T
G
S
Q
E
P
M
T
I
Y
F
T
S
G
T
Site 19
Y227
S
Q
E
P
M
T
I
Y
F
T
S
G
T
T
G
Site 20
S242
F
P
K
M
A
Q
H
S
Q
S
S
L
G
I
G
Site 21
S244
K
M
A
Q
H
S
Q
S
S
L
G
I
G
F
T
Site 22
T304
M
A
Q
F
D
T
D
T
F
L
D
T
L
T
T
Site 23
T308
D
T
D
T
F
L
D
T
L
T
T
Y
P
I
T
Site 24
Y312
F
L
D
T
L
T
T
Y
P
I
T
T
L
C
S
Site 25
Y335
V
Q
K
D
L
K
R
Y
K
F
K
S
L
R
H
Site 26
S339
L
K
R
Y
K
F
K
S
L
R
H
C
L
T
G
Site 27
T345
K
S
L
R
H
C
L
T
G
G
E
P
L
N
P
Site 28
T362
L
E
Q
W
R
V
Q
T
G
L
E
L
Y
E
G
Site 29
Y367
V
Q
T
G
L
E
L
Y
E
G
Y
G
Q
T
E
Site 30
S391
G
Q
E
I
K
P
G
S
M
G
K
G
M
L
P
Site 31
Y399
M
G
K
G
M
L
P
Y
D
V
Q
I
I
D
E
Site 32
Y435
P
F
C
F
F
S
K
Y
V
D
N
P
Q
K
T
Site 33
Y451
A
T
I
R
G
D
F
Y
V
T
G
D
R
G
V
Site 34
S500
E
H
P
A
V
V
E
S
A
V
V
S
S
P
D
Site 35
S505
V
E
S
A
V
V
S
S
P
D
Q
I
R
G
E
Site 36
S526
V
L
A
A
P
F
K
S
Y
N
P
E
K
L
T
Site 37
S543
L
Q
D
H
V
K
K
S
T
A
P
Y
K
Y
P
Site 38
Y547
V
K
K
S
T
A
P
Y
K
Y
P
R
K
V
E
Site 39
Y549
K
S
T
A
P
Y
K
Y
P
R
K
V
E
F
V
Site 40
T562
F
V
Q
E
L
P
K
T
I
T
G
K
I
K
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation