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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ELFN1
Full Name:
Extracellular leucine-rich repeat and fibronectin type-III domain-containing protein 1
Alias:
extracellular leucine-rich repeat and fibronectin type III domain containing 1; similar to slit homolog 1
Type:
Membrane protein
Mass (Da):
88057
Number AA:
806
UniProt ID:
P0C7U0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y438
L
V
L
G
A
V
Y
Y
C
L
R
R
R
R
R
Site 2
S461
A
S
A
A
A
A
G
S
L
K
K
T
I
I
E
Site 3
Y509
A
A
G
E
V
E
Q
Y
K
L
V
E
S
A
D
Site 4
T517
K
L
V
E
S
A
D
T
P
K
A
S
K
G
S
Site 5
S521
S
A
D
T
P
K
A
S
K
G
S
Y
M
E
S
Site 6
Y525
P
K
A
S
K
G
S
Y
M
E
S
S
V
A
E
Site 7
S528
S
K
G
S
Y
M
E
S
S
V
A
E
I
S
T
Site 8
S529
K
G
S
Y
M
E
S
S
V
A
E
I
S
T
I
Site 9
S556
N
C
I
D
A
L
K
S
E
S
T
S
F
Q
G
Site 10
T559
D
A
L
K
S
E
S
T
S
F
Q
G
V
K
S
Site 11
S560
A
L
K
S
E
S
T
S
F
Q
G
V
K
S
G
Site 12
S566
T
S
F
Q
G
V
K
S
G
P
V
S
V
A
E
Site 13
Y594
H
G
F
L
A
P
G
Y
K
D
A
F
G
H
S
Site 14
S601
Y
K
D
A
F
G
H
S
L
Q
R
H
H
S
V
Site 15
S607
H
S
L
Q
R
H
H
S
V
E
A
A
G
P
P
Site 16
S617
A
A
G
P
P
R
A
S
T
S
S
S
G
S
V
Site 17
T618
A
G
P
P
R
A
S
T
S
S
S
G
S
V
R
Site 18
S619
G
P
P
R
A
S
T
S
S
S
G
S
V
R
S
Site 19
S620
P
P
R
A
S
T
S
S
S
G
S
V
R
S
P
Site 20
S621
P
R
A
S
T
S
S
S
G
S
V
R
S
P
R
Site 21
S623
A
S
T
S
S
S
G
S
V
R
S
P
R
A
F
Site 22
S626
S
S
S
G
S
V
R
S
P
R
A
F
R
A
E
Site 23
Y647
A
A
A
A
E
A
K
Y
I
E
K
G
S
P
A
Site 24
S652
A
K
Y
I
E
K
G
S
P
A
A
D
A
I
L
Site 25
Y678
E
A
E
K
G
R
Q
Y
G
E
H
R
H
S
Y
Site 26
S684
Q
Y
G
E
H
R
H
S
Y
P
G
S
H
P
A
Site 27
Y685
Y
G
E
H
R
H
S
Y
P
G
S
H
P
A
E
Site 28
S688
H
R
H
S
Y
P
G
S
H
P
A
E
P
P
A
Site 29
S713
E
G
L
G
R
K
A
S
I
L
E
P
L
T
R
Site 30
T719
A
S
I
L
E
P
L
T
R
P
R
P
R
D
L
Site 31
Y728
P
R
P
R
D
L
A
Y
S
Q
L
S
P
Q
Y
Site 32
S729
R
P
R
D
L
A
Y
S
Q
L
S
P
Q
Y
H
Site 33
S732
D
L
A
Y
S
Q
L
S
P
Q
Y
H
S
L
S
Site 34
Y735
Y
S
Q
L
S
P
Q
Y
H
S
L
S
Y
S
S
Site 35
S737
Q
L
S
P
Q
Y
H
S
L
S
Y
S
S
S
P
Site 36
S739
S
P
Q
Y
H
S
L
S
Y
S
S
S
P
E
Y
Site 37
S741
Q
Y
H
S
L
S
Y
S
S
S
P
E
Y
T
C
Site 38
S743
H
S
L
S
Y
S
S
S
P
E
Y
T
C
R
A
Site 39
Y746
S
Y
S
S
S
P
E
Y
T
C
R
A
S
Q
S
Site 40
T747
Y
S
S
S
P
E
Y
T
C
R
A
S
Q
S
I
Site 41
S751
P
E
Y
T
C
R
A
S
Q
S
I
W
E
R
F
Site 42
S761
I
W
E
R
F
R
L
S
R
R
R
H
K
E
E
Site 43
Y796
D
L
H
D
I
L
D
Y
W
K
G
V
S
A
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation