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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RSPH10B
Full Name:
Radial spoke head 10 homolog B
Alias:
Type:
Mass (Da):
100635
Number AA:
870
UniProt ID:
P0C881
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
A
D
K
K
G
E
K
S
A
R
S
P
S
S
L
Site 2
S18
K
G
E
K
S
A
R
S
P
S
S
L
S
D
N
Site 3
S20
E
K
S
A
R
S
P
S
S
L
S
D
N
L
D
Site 4
S21
K
S
A
R
S
P
S
S
L
S
D
N
L
D
F
Site 5
S23
A
R
S
P
S
S
L
S
D
N
L
D
F
S
K
Site 6
S29
L
S
D
N
L
D
F
S
K
Q
D
G
N
T
T
Site 7
T35
F
S
K
Q
D
G
N
T
T
R
Q
E
M
S
P
Site 8
S41
N
T
T
R
Q
E
M
S
P
A
G
V
P
L
L
Site 9
T71
V
Q
Q
N
E
D
A
T
Q
Y
E
E
S
I
L
Site 10
Y73
Q
N
E
D
A
T
Q
Y
E
E
S
I
L
T
K
Site 11
T79
Q
Y
E
E
S
I
L
T
K
L
I
V
E
S
Y
Site 12
Y95
G
E
K
V
R
G
L
Y
E
G
E
G
F
A
A
Site 13
Y109
A
F
Q
G
G
C
T
Y
R
G
M
F
S
E
G
Site 14
Y124
L
M
H
G
Q
G
T
Y
I
W
A
D
G
L
K
Site 15
Y132
I
W
A
D
G
L
K
Y
E
G
D
F
V
K
N
Site 16
Y147
V
P
M
N
H
G
V
Y
T
W
P
D
G
S
M
Site 17
Y155
T
W
P
D
G
S
M
Y
E
G
E
V
V
N
G
Site 18
S193
G
K
R
H
G
K
G
S
I
Y
Y
N
Q
E
G
Site 19
Y195
R
H
G
K
G
S
I
Y
Y
N
Q
E
G
T
C
Site 20
Y221
K
G
W
G
I
R
C
Y
K
S
G
N
I
Y
E
Site 21
Y227
C
Y
K
S
G
N
I
Y
E
G
Q
W
E
D
N
Site 22
T246
E
G
R
M
R
W
L
T
T
N
E
E
Y
T
G
Site 23
T265
G
I
Q
N
G
F
G
T
H
T
W
F
L
K
R
Site 24
S275
W
F
L
K
R
I
R
S
S
Q
Y
P
L
R
N
Site 25
S276
F
L
K
R
I
R
S
S
Q
Y
P
L
R
N
E
Site 26
Y278
K
R
I
R
S
S
Q
Y
P
L
R
N
E
Y
I
Site 27
Y284
Q
Y
P
L
R
N
E
Y
I
G
E
F
V
N
G
Site 28
Y292
I
G
E
F
V
N
G
Y
R
H
G
R
G
K
F
Site 29
Y300
R
H
G
R
G
K
F
Y
Y
A
S
G
A
M
Y
Site 30
Y301
H
G
R
G
K
F
Y
Y
A
S
G
A
M
Y
D
Site 31
S303
R
G
K
F
Y
Y
A
S
G
A
M
Y
D
G
E
Site 32
Y307
Y
Y
A
S
G
A
M
Y
D
G
E
W
V
S
N
Site 33
T323
K
H
G
M
G
R
L
T
F
K
N
G
R
V
Y
Site 34
Y330
T
F
K
N
G
R
V
Y
E
G
A
F
S
N
D
Site 35
S335
R
V
Y
E
G
A
F
S
N
D
H
I
A
G
F
Site 36
S364
S
G
V
A
P
R
L
S
R
S
A
E
L
I
R
Site 37
S376
L
I
R
K
L
D
G
S
E
S
H
S
V
L
G
Site 38
S378
R
K
L
D
G
S
E
S
H
S
V
L
G
S
S
Site 39
S380
L
D
G
S
E
S
H
S
V
L
G
S
S
I
E
Site 40
S384
E
S
H
S
V
L
G
S
S
I
E
L
D
L
N
Site 41
Y397
L
N
L
L
L
D
M
Y
P
E
T
V
Q
P
E
Site 42
T400
L
L
D
M
Y
P
E
T
V
Q
P
E
E
K
K
Site 43
T418
Y
A
V
L
R
N
I
T
E
L
R
R
I
Y
S
Site 44
Y424
I
T
E
L
R
R
I
Y
S
F
Y
S
S
L
G
Site 45
S425
T
E
L
R
R
I
Y
S
F
Y
S
S
L
G
C
Site 46
Y427
L
R
R
I
Y
S
F
Y
S
S
L
G
C
G
H
Site 47
S428
R
R
I
Y
S
F
Y
S
S
L
G
C
G
H
S
Site 48
S429
R
I
Y
S
F
Y
S
S
L
G
C
G
H
S
L
Site 49
T439
C
G
H
S
L
D
N
T
F
L
M
T
K
L
H
Site 50
T462
K
F
H
H
H
K
L
T
L
A
D
M
D
R
I
Site 51
S471
A
D
M
D
R
I
L
S
A
N
N
D
I
P
V
Site 52
Y505
L
H
L
A
Y
H
I
Y
H
E
E
F
Q
K
R
Site 53
S513
H
E
E
F
Q
K
R
S
P
S
L
F
L
C
F
Site 54
S515
E
F
Q
K
R
S
P
S
L
F
L
C
F
T
K
Site 55
T546
L
F
R
E
Q
Q
R
T
L
Y
S
M
S
Y
M
Site 56
Y548
R
E
Q
Q
R
T
L
Y
S
M
S
Y
M
N
K
Site 57
S567
Y
L
A
Y
C
R
P
S
A
A
P
P
H
E
P
Site 58
Y612
A
E
D
N
R
F
I
Y
D
G
I
D
S
N
F
Site 59
S617
F
I
Y
D
G
I
D
S
N
F
E
P
E
L
V
Site 60
S647
V
T
D
Q
M
T
K
S
Y
T
N
V
P
A
D
Site 61
S657
N
V
P
A
D
D
V
S
G
N
K
H
E
T
I
Site 62
T666
N
K
H
E
T
I
Y
T
I
L
N
Q
D
A
Q
Site 63
S676
N
Q
D
A
Q
N
K
S
P
S
A
V
M
S
H
Site 64
S678
D
A
Q
N
K
S
P
S
A
V
M
S
H
E
S
Site 65
S682
K
S
P
S
A
V
M
S
H
E
S
D
A
A
H
Site 66
S685
S
A
V
M
S
H
E
S
D
A
A
H
S
D
S
Site 67
S690
H
E
S
D
A
A
H
S
D
S
A
R
S
S
S
Site 68
S692
S
D
A
A
H
S
D
S
A
R
S
S
S
S
K
Site 69
S695
A
H
S
D
S
A
R
S
S
S
S
K
L
E
L
Site 70
S696
H
S
D
S
A
R
S
S
S
S
K
L
E
L
S
Site 71
S697
S
D
S
A
R
S
S
S
S
K
L
E
L
S
P
Site 72
S698
D
S
A
R
S
S
S
S
K
L
E
L
S
P
D
Site 73
S703
S
S
S
K
L
E
L
S
P
D
V
N
K
I
R
Site 74
S712
D
V
N
K
I
R
K
S
E
P
K
I
K
K
S
Site 75
S719
S
E
P
K
I
K
K
S
V
S
H
E
R
V
S
Site 76
S721
P
K
I
K
K
S
V
S
H
E
R
V
S
K
M
Site 77
S726
S
V
S
H
E
R
V
S
K
M
N
F
K
L
T
Site 78
T733
S
K
M
N
F
K
L
T
G
K
G
I
T
F
F
Site 79
T738
K
L
T
G
K
G
I
T
F
F
S
S
E
S
K
Site 80
S741
G
K
G
I
T
F
F
S
S
E
S
K
K
Y
E
Site 81
S742
K
G
I
T
F
F
S
S
E
S
K
K
Y
E
R
Site 82
Y747
F
S
S
E
S
K
K
Y
E
R
P
K
D
D
R
Site 83
S794
I
R
A
D
R
L
R
S
T
A
Q
A
Q
Q
R
Site 84
T795
R
A
D
R
L
R
S
T
A
Q
A
Q
Q
R
K
Site 85
Y827
E
E
A
K
R
H
D
Y
E
V
D
I
T
V
L
Site 86
T832
H
D
Y
E
V
D
I
T
V
L
K
E
P
A
D
Site 87
S841
L
K
E
P
A
D
V
S
S
S
H
L
I
L
D
Site 88
T855
D
P
P
K
E
D
V
T
V
S
P
S
S
K
T
Site 89
S857
P
K
E
D
V
T
V
S
P
S
S
K
T
I
T
Site 90
S859
E
D
V
T
V
S
P
S
S
K
T
I
T
S
K
Site 91
S860
D
V
T
V
S
P
S
S
K
T
I
T
S
K
K
Site 92
T864
S
P
S
S
K
T
I
T
S
K
K
K
K
K
_
Site 93
S865
P
S
S
K
T
I
T
S
K
K
K
K
K
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation