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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GLI4
Full Name:
Zinc finger protein GLI4
Alias:
GLI family zinc finger 4; GLI-Kruppel family member GLI4; HKR4
Type:
Mass (Da):
41145
Number AA:
376
UniProt ID:
P10075
International Prot ID:
IPI00060440
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
A
L
G
D
I
Q
E
S
P
S
V
P
S
P
V
Site 2
S12
G
D
I
Q
E
S
P
S
V
P
S
P
V
S
L
Site 3
S15
Q
E
S
P
S
V
P
S
P
V
S
L
S
S
P
Site 4
S18
P
S
V
P
S
P
V
S
L
S
S
P
G
T
P
Site 5
S20
V
P
S
P
V
S
L
S
S
P
G
T
P
G
T
Site 6
S21
P
S
P
V
S
L
S
S
P
G
T
P
G
T
Q
Site 7
T24
V
S
L
S
S
P
G
T
P
G
T
Q
H
H
E
Site 8
T27
S
S
P
G
T
P
G
T
Q
H
H
E
P
Q
L
Site 9
S43
L
H
G
H
Q
H
G
S
P
G
S
S
P
K
V
Site 10
S46
H
Q
H
G
S
P
G
S
S
P
K
V
L
S
Q
Site 11
S47
Q
H
G
S
P
G
S
S
P
K
V
L
S
Q
P
Site 12
S52
G
S
S
P
K
V
L
S
Q
P
S
D
L
D
L
Site 13
T71
E
V
E
I
G
R
D
T
F
W
P
D
S
E
P
Site 14
S76
R
D
T
F
W
P
D
S
E
P
K
P
E
Q
A
Site 15
S86
K
P
E
Q
A
P
R
S
P
G
S
Q
A
P
D
Site 16
S89
Q
A
P
R
S
P
G
S
Q
A
P
D
E
G
A
Site 17
S102
G
A
G
G
A
L
R
S
L
L
R
S
L
P
R
Site 18
S106
A
L
R
S
L
L
R
S
L
P
R
R
A
R
C
Site 19
S114
L
P
R
R
A
R
C
S
A
G
F
G
P
E
S
Site 20
S121
S
A
G
F
G
P
E
S
S
A
E
R
P
A
G
Site 21
S122
A
G
F
G
P
E
S
S
A
E
R
P
A
G
Q
Site 22
T146
P
R
G
A
W
R
V
T
L
V
Q
Q
A
A
A
Site 23
S172
L
G
V
N
F
G
R
S
R
Q
G
S
A
R
G
Site 24
S176
F
G
R
S
R
Q
G
S
A
R
G
A
K
P
H
Site 25
S191
R
C
E
A
C
G
K
S
F
K
Y
N
S
L
L
Site 26
Y194
A
C
G
K
S
F
K
Y
N
S
L
L
L
K
H
Site 27
S196
G
K
S
F
K
Y
N
S
L
L
L
K
H
Q
R
Site 28
T206
L
K
H
Q
R
I
H
T
G
E
K
P
Y
A
C
Site 29
Y211
I
H
T
G
E
K
P
Y
A
C
H
E
C
G
K
Site 30
T234
I
Q
H
H
R
I
H
T
G
E
K
P
Y
E
C
Site 31
Y239
I
H
T
G
E
K
P
Y
E
C
G
Q
C
G
R
Site 32
S249
G
Q
C
G
R
A
F
S
H
S
S
H
F
T
Q
Site 33
S251
C
G
R
A
F
S
H
S
S
H
F
T
Q
H
L
Site 34
Y267
I
H
N
G
E
K
P
Y
K
C
G
E
C
G
Q
Site 35
S277
G
E
C
G
Q
A
F
S
Q
S
S
N
L
V
R
Site 36
S279
C
G
Q
A
F
S
Q
S
S
N
L
V
R
H
Q
Site 37
S280
G
Q
A
F
S
Q
S
S
N
L
V
R
H
Q
R
Site 38
T290
V
R
H
Q
R
L
H
T
G
E
K
P
Y
A
C
Site 39
Y295
L
H
T
G
E
K
P
Y
A
C
S
Q
C
G
K
Site 40
S308
G
K
A
F
I
W
S
S
V
L
I
E
H
Q
R
Site 41
T318
I
E
H
Q
R
I
H
T
G
E
K
P
Y
E
C
Site 42
Y323
I
H
T
G
E
K
P
Y
E
C
S
D
C
G
K
Site 43
S326
G
E
K
P
Y
E
C
S
D
C
G
K
A
F
R
Site 44
S336
G
K
A
F
R
G
R
S
H
F
F
R
H
L
R
Site 45
T344
H
F
F
R
H
L
R
T
H
T
G
E
K
P
F
Site 46
T346
F
R
H
L
R
T
H
T
G
E
K
P
F
A
C
Site 47
S364
G
K
A
F
G
Q
S
S
Q
L
I
Q
H
Q
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation