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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RAR-alpha
Full Name:
Retinoic acid receptor alpha
Alias:
Nuclear receptor subfamily 1 group B member 1
Type:
Transcription protein (receptor)
Mass (Da):
50771
Number AA:
462
UniProt ID:
P10276
International Prot ID:
IPI00020071
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0009986
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0001972
GO:0003708
GO:0043565
PhosphoSite+
KinaseNET
Biological Process:
GO:0030520
GO:0032689
GO:0032720
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
A
S
N
S
S
S
C
P
T
P
G
G
Site 2
S7
_
M
A
S
N
S
S
S
C
P
T
P
G
G
G
Site 3
T10
S
N
S
S
S
C
P
T
P
G
G
G
H
L
N
Site 4
Y19
G
G
G
H
L
N
G
Y
P
V
P
P
Y
A
F
Site 5
T43
S
P
P
G
A
L
T
T
L
Q
H
Q
L
P
V
Site 6
S51
L
Q
H
Q
L
P
V
S
G
Y
S
T
P
S
P
Site 7
Y53
H
Q
L
P
V
S
G
Y
S
T
P
S
P
A
T
Site 8
T55
L
P
V
S
G
Y
S
T
P
S
P
A
T
I
E
Site 9
S57
V
S
G
Y
S
T
P
S
P
A
T
I
E
T
Q
Site 10
T60
Y
S
T
P
S
P
A
T
I
E
T
Q
S
S
S
Site 11
T63
P
S
P
A
T
I
E
T
Q
S
S
S
S
E
E
Site 12
S65
P
A
T
I
E
T
Q
S
S
S
S
E
E
I
V
Site 13
S66
A
T
I
E
T
Q
S
S
S
S
E
E
I
V
P
Site 14
S68
I
E
T
Q
S
S
S
S
E
E
I
V
P
S
P
Site 15
S74
S
S
E
E
I
V
P
S
P
P
S
P
P
P
L
Site 16
S77
E
I
V
P
S
P
P
S
P
P
P
L
P
R
I
Site 17
Y85
P
P
P
L
P
R
I
Y
K
P
C
F
V
C
Q
Site 18
S96
F
V
C
Q
D
K
S
S
G
Y
H
Y
G
V
S
Site 19
Y100
D
K
S
S
G
Y
H
Y
G
V
S
A
C
E
G
Site 20
Y122
S
I
Q
K
N
M
V
Y
T
C
H
R
D
K
N
Site 21
S154
K
C
F
E
V
G
M
S
K
E
S
V
R
N
D
Site 22
S157
E
V
G
M
S
K
E
S
V
R
N
D
R
N
K
Site 23
S175
E
V
P
K
P
E
C
S
E
S
Y
T
L
T
P
Site 24
S177
P
K
P
E
C
S
E
S
Y
T
L
T
P
E
V
Site 25
T179
P
E
C
S
E
S
Y
T
L
T
P
E
V
G
E
Site 26
T181
C
S
E
S
Y
T
L
T
P
E
V
G
E
L
I
Site 27
T198
V
R
K
A
H
Q
E
T
F
P
A
L
C
Q
L
Site 28
Y208
A
L
C
Q
L
G
K
Y
T
T
N
N
S
S
E
Site 29
T209
L
C
Q
L
G
K
Y
T
T
N
N
S
S
E
Q
Site 30
S213
G
K
Y
T
T
N
N
S
S
E
Q
R
V
S
L
Site 31
S214
K
Y
T
T
N
N
S
S
E
Q
R
V
S
L
D
Site 32
S219
N
S
S
E
Q
R
V
S
L
D
I
D
L
W
D
Site 33
T233
D
K
F
S
E
L
S
T
K
C
I
I
K
T
V
Site 34
T275
I
L
I
L
R
I
C
T
R
Y
T
P
E
Q
D
Site 35
Y277
I
L
R
I
C
T
R
Y
T
P
E
Q
D
T
M
Site 36
T278
L
R
I
C
T
R
Y
T
P
E
Q
D
T
M
T
Site 37
T283
R
Y
T
P
E
Q
D
T
M
T
F
S
D
G
L
Site 38
T285
T
P
E
Q
D
T
M
T
F
S
D
G
L
T
L
Site 39
S287
E
Q
D
T
M
T
F
S
D
G
L
T
L
N
R
Site 40
T291
M
T
F
S
D
G
L
T
L
N
R
T
Q
M
H
Site 41
T295
D
G
L
T
L
N
R
T
Q
M
H
N
A
G
F
Site 42
Y362
L
L
E
A
L
K
V
Y
V
R
K
R
R
P
S
Site 43
S369
Y
V
R
K
R
R
P
S
R
P
H
M
F
P
K
Site 44
S386
M
K
I
T
D
L
R
S
I
S
A
K
G
A
E
Site 45
S388
I
T
D
L
R
S
I
S
A
K
G
A
E
R
V
Site 46
T397
K
G
A
E
R
V
I
T
L
K
M
E
I
P
G
Site 47
S405
L
K
M
E
I
P
G
S
M
P
P
L
I
Q
E
Site 48
T422
E
N
S
E
G
L
D
T
L
S
G
Q
P
G
G
Site 49
S424
S
E
G
L
D
T
L
S
G
Q
P
G
G
G
G
Site 50
S443
G
L
A
P
P
P
G
S
C
S
P
S
L
S
P
Site 51
S445
A
P
P
P
G
S
C
S
P
S
L
S
P
S
S
Site 52
S447
P
P
G
S
C
S
P
S
L
S
P
S
S
N
R
Site 53
S449
G
S
C
S
P
S
L
S
P
S
S
N
R
S
S
Site 54
S451
C
S
P
S
L
S
P
S
S
N
R
S
S
P
A
Site 55
S452
S
P
S
L
S
P
S
S
N
R
S
S
P
A
T
Site 56
S455
L
S
P
S
S
N
R
S
S
P
A
T
H
S
P
Site 57
S456
S
P
S
S
N
R
S
S
P
A
T
H
S
P
_
Site 58
S461
R
S
S
P
A
T
H
S
P
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation