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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HIST1H1E
Full Name:
Histone H1.4
Alias:
H1.4; H14; H1F4; Histone cluster 1, H1e; Histone H1b
Type:
DNA binding protein
Mass (Da):
21865
Number AA:
219
UniProt ID:
P10412
International Prot ID:
IPI00217467
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000786
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006334
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S2
_
_
_
_
_
_
M
S
E
T
A
P
A
A
P
Site 2
T4
_
_
_
_
M
S
E
T
A
P
A
A
P
A
A
Site 3
T18
A
P
A
P
A
E
K
T
P
V
K
K
K
A
R
Site 4
S27
V
K
K
K
A
R
K
S
A
G
A
A
K
R
K
Site 5
S36
G
A
A
K
R
K
A
S
G
P
P
V
S
E
L
Site 6
S41
K
A
S
G
P
P
V
S
E
L
I
T
K
A
V
Site 7
S51
I
T
K
A
V
A
A
S
K
E
R
S
G
V
S
Site 8
S55
V
A
A
S
K
E
R
S
G
V
S
L
A
A
L
Site 9
S58
S
K
E
R
S
G
V
S
L
A
A
L
K
K
A
Site 10
Y71
K
A
L
A
A
A
G
Y
D
V
E
K
N
N
S
Site 11
S78
Y
D
V
E
K
N
N
S
R
I
K
L
G
L
K
Site 12
S86
R
I
K
L
G
L
K
S
L
V
S
K
G
T
L
Site 13
T92
K
S
L
V
S
K
G
T
L
V
Q
T
K
G
T
Site 14
T99
T
L
V
Q
T
K
G
T
G
A
S
G
S
F
K
Site 15
S102
Q
T
K
G
T
G
A
S
G
S
F
K
L
N
K
Site 16
S104
K
G
T
G
A
S
G
S
F
K
L
N
K
K
A
Site 17
T146
K
K
A
T
G
A
A
T
P
K
K
S
A
K
K
Site 18
S150
G
A
A
T
P
K
K
S
A
K
K
T
P
K
K
Site 19
T154
P
K
K
S
A
K
K
T
P
K
K
A
K
K
P
Site 20
S172
A
G
A
K
K
A
K
S
P
K
K
A
K
A
A
Site 21
S187
K
P
K
K
A
P
K
S
P
A
K
A
K
A
V
Site 22
T203
P
K
A
A
K
P
K
T
A
K
P
K
A
A
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation