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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CHGA
Full Name:
Chromogranin-A
Alias:
Pituitary secretaory protein I; SP-I
Type:
Vesicle protein; Adhesion; Secreted protein
Mass (Da):
50688
Number AA:
457
UniProt ID:
P10645
International Prot ID:
IPI00290315
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
Uniprot
OncoNet
Molecular Function:
GO:0005509
PhosphoSite+
KinaseNET
Biological Process:
GO:0008217
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S23
V
T
A
L
P
V
N
S
P
M
N
K
G
D
T
Site 2
T30
S
P
M
N
K
G
D
T
E
V
M
K
C
I
V
Site 3
S45
E
V
I
S
D
T
L
S
K
P
S
P
M
P
V
Site 4
S48
S
D
T
L
S
K
P
S
P
M
P
V
S
Q
E
Site 5
S53
K
P
S
P
M
P
V
S
Q
E
C
F
E
T
L
Site 6
T59
V
S
Q
E
C
F
E
T
L
R
G
D
E
R
I
Site 7
S68
R
G
D
E
R
I
L
S
I
L
R
H
Q
N
L
Site 8
S105
S
G
F
E
D
E
L
S
E
V
L
E
N
Q
S
Site 9
S112
S
E
V
L
E
N
Q
S
S
Q
A
E
L
K
E
Site 10
S113
E
V
L
E
N
Q
S
S
Q
A
E
L
K
E
A
Site 11
S126
E
A
V
E
E
P
S
S
K
D
V
M
E
K
R
Site 12
S136
V
M
E
K
R
E
D
S
K
E
A
E
K
S
G
Site 13
S142
D
S
K
E
A
E
K
S
G
E
A
T
D
G
A
Site 14
T146
A
E
K
S
G
E
A
T
D
G
A
R
P
Q
A
Site 15
T181
E
E
E
E
E
E
A
T
N
T
H
P
P
A
S
Site 16
T183
E
E
E
E
A
T
N
T
H
P
P
A
S
L
P
Site 17
S188
T
N
T
H
P
P
A
S
L
P
S
Q
K
Y
P
Site 18
Y194
A
S
L
P
S
Q
K
Y
P
G
P
Q
A
E
G
Site 19
S203
G
P
Q
A
E
G
D
S
E
G
L
S
Q
G
L
Site 20
S207
E
G
D
S
E
G
L
S
Q
G
L
V
D
R
E
Site 21
S218
V
D
R
E
K
G
L
S
A
E
P
G
W
Q
A
Site 22
T251
V
P
E
E
E
G
P
T
V
V
L
N
P
H
P
Site 23
S259
V
V
L
N
P
H
P
S
L
G
Y
K
E
I
R
Site 24
S270
K
E
I
R
K
G
E
S
R
S
E
A
L
A
V
Site 25
S300
G
K
G
E
Q
E
H
S
Q
Q
K
E
E
E
E
Site 26
S322
G
L
F
R
G
G
K
S
G
E
L
E
Q
E
E
Site 27
S333
E
Q
E
E
E
R
L
S
K
E
W
E
D
S
K
Site 28
S339
L
S
K
E
W
E
D
S
K
R
W
S
K
M
D
Site 29
T353
D
Q
L
A
K
E
L
T
A
E
K
R
L
E
G
Site 30
S370
E
E
E
D
N
R
D
S
S
M
K
L
S
F
R
Site 31
S371
E
E
D
N
R
D
S
S
M
K
L
S
F
R
A
Site 32
S375
R
D
S
S
M
K
L
S
F
R
A
R
A
Y
G
Site 33
Y381
L
S
F
R
A
R
A
Y
G
F
R
G
P
G
P
Site 34
S397
L
R
R
G
W
R
P
S
S
R
E
D
S
L
E
Site 35
S398
R
R
G
W
R
P
S
S
R
E
D
S
L
E
A
Site 36
S402
R
P
S
S
R
E
D
S
L
E
A
G
L
P
L
Site 37
Y414
L
P
L
Q
V
R
G
Y
P
E
E
K
K
E
E
Site 38
S424
E
K
K
E
E
E
G
S
A
N
R
R
P
E
D
Site 39
S436
P
E
D
Q
E
L
E
S
L
S
A
I
E
A
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation