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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RBP3
Full Name:
Retinol-binding protein 3
Alias:
Interphotoreceptor retinoid-binding protein;Interstitial retinol-binding protein
Type:
Mass (Da):
135363
Number AA:
1247
UniProt ID:
P10745
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S63
I
K
S
H
E
I
L
S
I
S
D
P
Q
T
L
Site 2
S65
S
H
E
I
L
S
I
S
D
P
Q
T
L
A
S
Site 3
S90
N
D
P
R
L
V
I
S
Y
E
P
S
T
P
E
Site 4
Y91
D
P
R
L
V
I
S
Y
E
P
S
T
P
E
P
Site 5
S94
L
V
I
S
Y
E
P
S
T
P
E
P
P
P
Q
Site 6
T95
V
I
S
Y
E
P
S
T
P
E
P
P
P
Q
V
Site 7
S107
P
Q
V
P
A
L
T
S
L
S
E
E
E
L
L
Site 8
S185
S
G
I
P
Y
I
I
S
Y
L
H
P
G
N
T
Site 9
T198
N
T
I
L
H
V
D
T
I
Y
N
R
P
S
N
Site 10
Y200
I
L
H
V
D
T
I
Y
N
R
P
S
N
T
T
Site 11
T208
N
R
P
S
N
T
T
T
E
I
W
T
L
P
Q
Site 12
T259
A
I
V
V
G
E
R
T
G
G
G
A
L
D
L
Site 13
S274
R
K
L
R
I
G
E
S
D
F
F
F
T
V
P
Site 14
S293
L
G
P
L
G
G
G
S
Q
T
W
E
G
S
G
Site 15
T295
P
L
G
G
G
S
Q
T
W
E
G
S
G
V
L
Site 16
S299
G
S
Q
T
W
E
G
S
G
V
L
P
C
V
G
Site 17
Y340
L
Q
E
V
L
K
D
Y
Y
T
L
V
D
R
V
Site 18
Y341
Q
E
V
L
K
D
Y
Y
T
L
V
D
R
V
P
Site 19
T342
E
V
L
K
D
Y
Y
T
L
V
D
R
V
P
T
Site 20
S360
H
L
A
S
M
D
F
S
T
V
V
S
E
E
D
Site 21
S364
M
D
F
S
T
V
V
S
E
E
D
L
V
T
K
Site 22
T370
V
S
E
E
D
L
V
T
K
L
N
A
G
L
Q
Site 23
T393
L
V
R
A
I
G
P
T
E
T
P
S
W
P
A
Site 24
T395
R
A
I
G
P
T
E
T
P
S
W
P
A
P
D
Site 25
S397
I
G
P
T
E
T
P
S
W
P
A
P
D
A
A
Site 26
S408
P
D
A
A
A
E
D
S
P
G
V
A
P
E
L
Site 27
S487
H
N
P
G
G
P
S
S
A
V
P
L
L
L
S
Site 28
T509
G
P
V
H
L
F
T
T
Y
D
R
R
T
N
I
Site 29
Y510
P
V
H
L
F
T
T
Y
D
R
R
T
N
I
T
Site 30
Y531
M
E
L
P
G
P
R
Y
S
T
Q
R
G
V
Y
Site 31
S532
E
L
P
G
P
R
Y
S
T
Q
R
G
V
Y
L
Site 32
T533
L
P
G
P
R
Y
S
T
Q
R
G
V
Y
L
L
Site 33
Y538
Y
S
T
Q
R
G
V
Y
L
L
T
S
H
R
T
Site 34
S542
R
G
V
Y
L
L
T
S
H
R
T
A
T
A
A
Site 35
T547
L
T
S
H
R
T
A
T
A
A
E
E
F
A
F
Site 36
T578
G
N
L
L
H
T
R
T
V
P
L
L
D
T
P
Site 37
Y651
G
H
L
L
E
A
H
Y
A
R
P
E
V
V
G
Site 38
S694
T
A
D
L
Q
E
V
S
G
D
H
R
L
L
V
Site 39
S722
P
P
P
P
A
V
P
S
P
E
E
L
T
Y
L
Site 40
Y728
P
S
P
E
E
L
T
Y
L
I
E
A
L
F
K
Site 41
Y784
A
L
V
I
D
L
R
Y
N
P
G
S
Y
S
T
Site 42
S788
D
L
R
Y
N
P
G
S
Y
S
T
A
I
P
L
Site 43
S790
R
Y
N
P
G
S
Y
S
T
A
I
P
L
L
C
Site 44
S811
E
P
R
Q
H
L
Y
S
V
F
D
R
A
T
S
Site 45
T817
Y
S
V
F
D
R
A
T
S
K
V
T
E
V
W
Site 46
S818
S
V
F
D
R
A
T
S
K
V
T
E
V
W
T
Site 47
Y834
P
Q
V
A
G
Q
R
Y
G
S
H
K
D
L
Y
Site 48
S836
V
A
G
Q
R
Y
G
S
H
K
D
L
Y
I
L
Site 49
Y841
Y
G
S
H
K
D
L
Y
I
L
M
S
H
T
S
Site 50
S845
K
D
L
Y
I
L
M
S
H
T
S
G
S
A
A
Site 51
T866
M
Q
D
L
Q
R
A
T
V
I
G
E
P
T
A
Site 52
Y890
Q
V
G
S
S
P
L
Y
A
S
M
P
T
Q
M
Site 53
S892
G
S
S
P
L
Y
A
S
M
P
T
Q
M
A
M
Site 54
S966
A
K
M
A
T
K
L
S
G
L
Q
S
R
Y
S
Site 55
S970
T
K
L
S
G
L
Q
S
R
Y
S
R
V
T
S
Site 56
Y972
L
S
G
L
Q
S
R
Y
S
R
V
T
S
E
V
Site 57
S973
S
G
L
Q
S
R
Y
S
R
V
T
S
E
V
A
Site 58
T976
Q
S
R
Y
S
R
V
T
S
E
V
A
L
A
E
Site 59
S977
S
R
Y
S
R
V
T
S
E
V
A
L
A
E
I
Site 60
S993
G
A
D
L
Q
M
L
S
G
D
P
H
L
K
A
Site 61
Y1112
P
V
L
L
D
K
I
Y
S
R
P
D
D
S
V
Site 62
S1113
V
L
L
D
K
I
Y
S
R
P
D
D
S
V
S
Site 63
S1118
I
Y
S
R
P
D
D
S
V
S
E
L
W
T
H
Site 64
S1120
S
R
P
D
D
S
V
S
E
L
W
T
H
A
Q
Site 65
Y1133
A
Q
V
V
G
E
R
Y
G
S
K
K
S
M
V
Site 66
S1138
E
R
Y
G
S
K
K
S
M
V
I
L
T
S
S
Site 67
Y1156
G
T
A
E
E
F
T
Y
I
M
K
R
L
G
R
Site 68
Y1189
H
V
D
D
T
N
L
Y
L
T
I
P
T
A
R
Site 69
S1197
L
T
I
P
T
A
R
S
V
G
A
S
D
G
S
Site 70
S1201
T
A
R
S
V
G
A
S
D
G
S
S
W
E
G
Site 71
S1204
S
V
G
A
S
D
G
S
S
W
E
G
V
G
V
Site 72
S1205
V
G
A
S
D
G
S
S
W
E
G
V
G
V
T
Site 73
S1240
N
Q
L
R
V
K
R
S
P
G
L
Q
D
H
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation