PhosphoNET

           
Protein Info 
   
Short Name:  CD28
Full Name:  T-cell-specific surface glycoprotein CD28
Alias:  TP44
Type:  Receptor
Mass (Da):  25066
Number AA:  220
UniProt ID:  P10747
International Prot ID:  IPI00022339
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005829  GO:0009897  GO:0005887 Uniprot OncoNet
Molecular Function:  GO:0015026  GO:0042802   PhosphoSite+ KinaseNET
Biological Process:  GO:0007166  GO:0042089  GO:0006959 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S189KRSRLLHSDYMNMTP
Site 2Y191SRLLHSDYMNMTPRR
Site 3T195HSDYMNMTPRRPGPT
Site 4T202TPRRPGPTRKHYQPY
Site 5Y206PGPTRKHYQPYAPPR
Site 6Y209TRKHYQPYAPPRDFA
Site 7Y218PPRDFAAYRS_____
Site 8S220RDFAAYRS_______
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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