KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
esterase D
Full Name:
S-formylglutathione hydrolase
Alias:
ESD; ESTD; esterase D/formylglutathione hydrolase
Type:
EC 3.1.2.12; Hydrolase
Mass (Da):
31463
Number AA:
282
UniProt ID:
P10768
International Prot ID:
IPI00411706
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016023
Uniprot
OncoNet
Molecular Function:
GO:0018738
GO:0004091
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y35
C
K
M
K
F
A
V
Y
L
P
P
K
A
E
T
Site 2
S65
E
Q
N
F
I
S
K
S
G
Y
H
Q
S
A
S
Site 3
S70
S
K
S
G
Y
H
Q
S
A
S
E
H
G
L
V
Site 4
S72
S
G
Y
H
Q
S
A
S
E
H
G
L
V
V
I
Site 5
S84
V
V
I
A
P
D
T
S
P
R
G
C
N
I
K
Site 6
S96
N
I
K
G
E
D
E
S
W
D
F
G
T
G
A
Site 7
T101
D
E
S
W
D
F
G
T
G
A
G
F
Y
V
D
Site 8
Y106
F
G
T
G
A
G
F
Y
V
D
A
T
E
D
P
Site 9
Y118
E
D
P
W
K
T
N
Y
R
M
Y
S
Y
V
T
Site 10
Y121
W
K
T
N
Y
R
M
Y
S
Y
V
T
E
E
L
Site 11
S122
K
T
N
Y
R
M
Y
S
Y
V
T
E
E
L
P
Site 12
Y123
T
N
Y
R
M
Y
S
Y
V
T
E
E
L
P
Q
Site 13
S144
P
V
D
P
Q
R
M
S
I
F
G
H
S
M
G
Site 14
S149
R
M
S
I
F
G
H
S
M
G
G
H
G
A
L
Site 15
Y166
A
L
K
N
P
G
K
Y
K
S
V
S
A
F
A
Site 16
S168
K
N
P
G
K
Y
K
S
V
S
A
F
A
P
I
Site 17
Y191
G
K
K
A
F
S
G
Y
L
G
T
D
Q
S
K
Site 18
T205
K
W
K
A
Y
D
A
T
H
L
V
K
S
Y
P
Site 19
S210
D
A
T
H
L
V
K
S
Y
P
G
S
Q
L
D
Site 20
Y211
A
T
H
L
V
K
S
Y
P
G
S
Q
L
D
I
Site 21
S214
L
V
K
S
Y
P
G
S
Q
L
D
I
L
I
D
Site 22
Y258
V
F
R
L
Q
E
G
Y
D
H
S
Y
Y
F
I
Site 23
Y262
Q
E
G
Y
D
H
S
Y
Y
F
I
A
T
F
I
Site 24
Y263
E
G
Y
D
H
S
Y
Y
F
I
A
T
F
I
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation