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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HSPD1
Full Name:
60 kDa heat shock protein, mitochondrial
Alias:
60 kDa chaperonin; CH60; CPN60; Heat shock protein 60; HSP-60; HuCHA60; Mitochondrial matrix protein P1; P60 lymphocyte protein
Type:
Chaperone protein
Mass (Da):
61055
Number AA:
573
UniProt ID:
P10809
International Prot ID:
IPI00784154
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0009986
GO:0005905
GO:0030135
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0016887
GO:0003688
PhosphoSite+
KinaseNET
Biological Process:
GO:0006458
GO:0002368
GO:0042100
Phosida
TranscriptoNet
STRING
Kinexus Products
60 kDa heat shock protein, mitochondrial pan-specific antibody AB-NN059-3#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NN059-3#60 kDa heat shock protein, mitochondrial pan-specific antibody AB-NN059-4#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NN059-4#60 kDa heat shock protein, mitochondrial pan-specific antibody AB-NN059-5#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NN059-5
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
F
R
Q
M
R
P
V
S
R
V
L
A
P
H
L
Site 2
Y26
A
P
H
L
T
R
A
Y
A
K
D
V
K
F
G
Site 3
T61
T
M
G
P
K
G
R
T
V
I
I
E
Q
S
W
Site 4
S67
R
T
V
I
I
E
Q
S
W
G
S
P
K
V
T
Site 5
S70
I
I
E
Q
S
W
G
S
P
K
V
T
K
D
G
Site 6
T74
S
W
G
S
P
K
V
T
K
D
G
V
T
V
A
Site 7
T79
K
V
T
K
D
G
V
T
V
A
K
S
I
D
L
Site 8
S83
D
G
V
T
V
A
K
S
I
D
L
K
D
K
Y
Site 9
Y90
S
I
D
L
K
D
K
Y
K
N
I
G
A
K
L
Site 10
T105
V
Q
D
V
A
N
N
T
N
E
E
A
G
D
G
Site 11
T163
K
K
Q
S
K
P
V
T
T
P
E
E
I
A
Q
Site 12
T164
K
Q
S
K
P
V
T
T
P
E
E
I
A
Q
V
Site 13
S187
K
E
I
G
N
I
I
S
D
A
M
K
K
V
G
Site 14
T200
V
G
R
K
G
V
I
T
V
K
D
G
K
T
L
Site 15
T206
I
T
V
K
D
G
K
T
L
N
D
E
L
E
I
Site 16
Y223
G
M
K
F
D
R
G
Y
I
S
P
Y
F
I
N
Site 17
S225
K
F
D
R
G
Y
I
S
P
Y
F
I
N
T
S
Site 18
Y227
D
R
G
Y
I
S
P
Y
F
I
N
T
S
K
G
Site 19
S232
S
P
Y
F
I
N
T
S
K
G
Q
K
C
E
F
Site 20
Y243
K
C
E
F
Q
D
A
Y
V
L
L
S
E
K
K
Site 21
S247
Q
D
A
Y
V
L
L
S
E
K
K
I
S
S
I
Site 22
S253
L
S
E
K
K
I
S
S
I
Q
S
I
V
P
A
Site 23
T331
V
F
G
E
E
G
L
T
L
N
L
E
D
V
Q
Site 24
T381
I
I
E
Q
L
D
V
T
T
S
E
Y
E
K
E
Site 25
S383
E
Q
L
D
V
T
T
S
E
Y
E
K
E
K
L
Site 26
Y385
L
D
V
T
T
S
E
Y
E
K
E
K
L
N
E
Site 27
S398
N
E
R
L
A
K
L
S
D
G
V
A
V
L
K
Site 28
T409
A
V
L
K
V
G
G
T
S
D
V
E
V
N
E
Site 29
S410
V
L
K
V
G
G
T
S
D
V
E
V
N
E
K
Site 30
T422
N
E
K
K
D
R
V
T
D
A
L
N
A
T
R
Site 31
S453
R
C
I
P
A
L
D
S
L
T
P
A
N
E
D
Site 32
T455
I
P
A
L
D
S
L
T
P
A
N
E
D
Q
K
Site 33
T471
G
I
E
I
I
K
R
T
L
K
I
P
A
M
T
Site 34
T478
T
L
K
I
P
A
M
T
I
A
K
N
A
G
V
Site 35
S497
I
V
E
K
I
M
Q
S
S
S
E
V
G
Y
D
Site 36
S499
E
K
I
M
Q
S
S
S
E
V
G
Y
D
A
M
Site 37
Y503
Q
S
S
S
E
V
G
Y
D
A
M
A
G
D
F
Site 38
T522
E
K
G
I
I
D
P
T
K
V
V
R
T
A
L
Site 39
T540
A
G
V
A
S
L
L
T
T
A
E
V
V
V
T
Site 40
T547
T
T
A
E
V
V
V
T
E
I
P
K
E
E
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation