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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ACP2
Full Name:
Lysosomal acid phosphatase
Alias:
Type:
Mass (Da):
48344
Number AA:
423
UniProt ID:
P11117
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
A
G
K
R
S
G
W
S
R
A
A
L
L
Q
L
Site 2
T28
N
L
V
V
M
P
P
T
R
A
R
S
L
R
F
Site 3
T37
A
R
S
L
R
F
V
T
L
L
Y
R
H
G
D
Site 4
Y40
L
R
F
V
T
L
L
Y
R
H
G
D
R
S
P
Site 5
S46
L
Y
R
H
G
D
R
S
P
V
K
T
Y
P
K
Site 6
T50
G
D
R
S
P
V
K
T
Y
P
K
D
P
Y
Q
Site 7
Y56
K
T
Y
P
K
D
P
Y
Q
E
E
E
W
P
Q
Site 8
T69
P
Q
G
F
G
Q
L
T
K
E
G
M
L
Q
H
Site 9
Y87
G
Q
A
L
R
Q
R
Y
H
G
F
L
N
T
S
Site 10
Y95
H
G
F
L
N
T
S
Y
H
R
Q
E
V
Y
V
Site 11
Y101
S
Y
H
R
Q
E
V
Y
V
R
S
T
D
F
D
Site 12
T105
Q
E
V
Y
V
R
S
T
D
F
D
R
T
L
M
Site 13
T110
R
S
T
D
F
D
R
T
L
M
S
A
E
A
N
Site 14
S113
D
F
D
R
T
L
M
S
A
E
A
N
L
A
G
Site 15
T147
P
V
H
T
V
P
I
T
E
D
R
L
L
K
F
Site 16
Y162
P
L
G
P
C
P
R
Y
E
Q
L
Q
N
E
T
Site 17
T172
L
Q
N
E
T
R
Q
T
P
E
Y
Q
N
E
S
Site 18
Y175
E
T
R
Q
T
P
E
Y
Q
N
E
S
S
R
N
Site 19
S179
T
P
E
Y
Q
N
E
S
S
R
N
A
Q
F
L
Site 20
Y207
L
E
T
V
W
N
V
Y
D
T
L
F
C
E
Q
Site 21
S225
L
R
L
P
P
W
A
S
P
Q
T
M
Q
R
L
Site 22
T228
P
P
W
A
S
P
Q
T
M
Q
R
L
S
R
L
Site 23
S233
P
Q
T
M
Q
R
L
S
R
L
K
D
F
S
F
Site 24
T269
A
Q
I
R
K
N
L
T
L
M
A
T
T
S
Q
Site 25
T273
K
N
L
T
L
M
A
T
T
S
Q
L
P
K
L
Site 26
Y300
L
Q
M
A
L
D
V
Y
N
G
E
Q
A
P
Y
Site 27
Y307
Y
N
G
E
Q
A
P
Y
A
S
C
H
I
F
E
Site 28
Y316
S
C
H
I
F
E
L
Y
Q
E
D
S
G
N
F
Site 29
S320
F
E
L
Y
Q
E
D
S
G
N
F
S
V
E
M
Site 30
S324
Q
E
D
S
G
N
F
S
V
E
M
Y
F
R
N
Site 31
Y328
G
N
F
S
V
E
M
Y
F
R
N
E
S
D
K
Site 32
S333
E
M
Y
F
R
N
E
S
D
K
A
P
W
P
L
Site 33
S341
D
K
A
P
W
P
L
S
L
P
G
C
P
H
R
Site 34
T358
L
Q
D
F
L
R
L
T
E
P
V
V
P
K
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation