PhosphoNET

           
Protein Info 
   
Short Name:  nAChRB1
Full Name:  Acetylcholine receptor subunit beta
Alias:  Acetylcholine receptor beta; ACHB; ACHRB; Cholinergic receptor, nicotinic, beta 1 (muscle); CHRNB; CMS1D; CMS2A; SCCMS
Type:  Ion channel, cation
Mass (Da):  56698
Number AA:  501
UniProt ID:  P11230
International Prot ID:  IPI00298986
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0030054  GO:0005892  GO:0045211 Uniprot OncoNet
Molecular Function:  GO:0042166  GO:0004872   PhosphoSite+ KinaseNET
Biological Process:  GO:0035095  GO:0006812  GO:0006936 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y78EEMSTKVYLDLEWTD
Site 2T84VYLDLEWTDYRLSWD
Site 3Y86LDLEWTDYRLSWDPA
Site 4T339LHHRSPHTHQMPLWV
Site 5Y357FIHKLPLYLRLKRPK
Site 6S377MPEPPHCSSPGSGWG
Site 7S378PEPPHCSSPGSGWGR
Site 8S381PHCSSPGSGWGRGTD
Site 9T387GSGWGRGTDEYFIRK
Site 10Y390WGRGTDEYFIRKPPS
Site 11S397YFIRKPPSDFLFPKP
Site 12S412NRFQPELSAPDLRRF
Site 13S438PELREVVSSISYIAR
Site 14S439ELREVVSSISYIARQ
Site 15S441REVVSSISYIARQLQ
Site 16Y442EVVSSISYIARQLQE
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


2019 Kinexus Bioinformatics Corporation