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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ERG
Full Name:
Transcriptional regulator ERG
Alias:
Erg-3; P55; TMPRSS2-ERG prostate cancer specific; Transcriptional regulator ERG (transforming protein ERG); Transforming protein ERG; V-ets avian erythroblastosis virus E26 oncogene related; V-ets erythroblastosis virus E26 oncogene; V-ets erythroblastosis virus E26 oncogene like; V-ets erythroblastosis virus E26 oncogene like (avian)
Type:
Transcription protein
Mass (Da):
54608
Number AA:
486
UniProt ID:
P11308
International Prot ID:
IPI00220990
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0005515
GO:0004871
PhosphoSite+
KinaseNET
Biological Process:
GO:0008283
GO:0007275
GO:0006468
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S17
A
H
I
K
E
A
L
S
V
V
S
E
D
Q
S
Site 2
S20
K
E
A
L
S
V
V
S
E
D
Q
S
L
F
E
Site 3
S24
S
V
V
S
E
D
Q
S
L
F
E
C
A
Y
G
Site 4
Y30
Q
S
L
F
E
C
A
Y
G
T
P
H
L
A
K
Site 5
T32
L
F
E
C
A
Y
G
T
P
H
L
A
K
T
E
Site 6
T38
G
T
P
H
L
A
K
T
E
M
T
A
S
S
S
Site 7
T41
H
L
A
K
T
E
M
T
A
S
S
S
S
D
Y
Site 8
S43
A
K
T
E
M
T
A
S
S
S
S
D
Y
G
Q
Site 9
S44
K
T
E
M
T
A
S
S
S
S
D
Y
G
Q
T
Site 10
S46
E
M
T
A
S
S
S
S
D
Y
G
Q
T
S
K
Site 11
Y48
T
A
S
S
S
S
D
Y
G
Q
T
S
K
M
S
Site 12
T51
S
S
S
D
Y
G
Q
T
S
K
M
S
P
R
V
Site 13
S52
S
S
D
Y
G
Q
T
S
K
M
S
P
R
V
P
Site 14
S55
Y
G
Q
T
S
K
M
S
P
R
V
P
Q
Q
D
Site 15
S65
V
P
Q
Q
D
W
L
S
Q
P
P
A
R
V
T
Site 16
T72
S
Q
P
P
A
R
V
T
I
K
M
E
C
N
P
Site 17
S80
I
K
M
E
C
N
P
S
Q
V
N
G
S
R
N
Site 18
S85
N
P
S
Q
V
N
G
S
R
N
S
P
D
E
C
Site 19
S88
Q
V
N
G
S
R
N
S
P
D
E
C
S
V
A
Site 20
S93
R
N
S
P
D
E
C
S
V
A
K
G
G
K
M
Site 21
S103
K
G
G
K
M
V
G
S
P
D
T
V
G
M
N
Site 22
T106
K
M
V
G
S
P
D
T
V
G
M
N
Y
G
S
Site 23
Y111
P
D
T
V
G
M
N
Y
G
S
Y
M
E
E
K
Site 24
Y114
V
G
M
N
Y
G
S
Y
M
E
E
K
H
M
P
Site 25
Y157
L
E
W
A
V
K
E
Y
G
L
P
D
V
N
I
Site 26
T187
K
D
D
F
Q
R
L
T
P
S
Y
N
A
D
I
Site 27
S189
D
F
Q
R
L
T
P
S
Y
N
A
D
I
L
L
Site 28
Y190
F
Q
R
L
T
P
S
Y
N
A
D
I
L
L
S
Site 29
T205
H
L
H
Y
L
R
E
T
P
L
P
H
L
T
S
Site 30
S212
T
P
L
P
H
L
T
S
D
D
V
D
K
A
L
Site 31
S222
V
D
K
A
L
Q
N
S
P
R
L
M
H
A
R
Site 32
S242
A
F
I
F
P
N
T
S
V
Y
P
E
A
T
Q
Site 33
Y244
I
F
P
N
T
S
V
Y
P
E
A
T
Q
R
I
Site 34
T248
T
S
V
Y
P
E
A
T
Q
R
I
T
T
R
P
Site 35
T252
P
E
A
T
Q
R
I
T
T
R
P
D
L
P
Y
Site 36
T253
E
A
T
Q
R
I
T
T
R
P
D
L
P
Y
E
Site 37
Y259
T
T
R
P
D
L
P
Y
E
P
P
R
R
S
A
Site 38
S265
P
Y
E
P
P
R
R
S
A
W
T
G
H
G
H
Site 39
T268
P
P
R
R
S
A
W
T
G
H
G
H
P
T
P
Site 40
T274
W
T
G
H
G
H
P
T
P
Q
S
K
A
A
Q
Site 41
S277
H
G
H
P
T
P
Q
S
K
A
A
Q
P
S
P
Site 42
S283
Q
S
K
A
A
Q
P
S
P
S
T
V
P
K
T
Site 43
S285
K
A
A
Q
P
S
P
S
T
V
P
K
T
E
D
Site 44
T286
A
A
Q
P
S
P
S
T
V
P
K
T
E
D
Q
Site 45
T290
S
P
S
T
V
P
K
T
E
D
Q
R
P
Q
L
Site 46
Y300
Q
R
P
Q
L
D
P
Y
Q
I
L
G
P
T
S
Site 47
S307
Y
Q
I
L
G
P
T
S
S
R
L
A
N
P
G
Site 48
S308
Q
I
L
G
P
T
S
S
R
L
A
N
P
G
S
Site 49
S315
S
R
L
A
N
P
G
S
G
Q
I
Q
L
W
Q
Site 50
S329
Q
F
L
L
E
L
L
S
D
S
S
N
S
S
C
Site 51
S332
L
E
L
L
S
D
S
S
N
S
S
C
I
T
W
Site 52
S334
L
L
S
D
S
S
N
S
S
C
I
T
W
E
G
Site 53
S335
L
S
D
S
S
N
S
S
C
I
T
W
E
G
T
Site 54
T338
S
S
N
S
S
C
I
T
W
E
G
T
N
G
E
Site 55
T349
T
N
G
E
F
K
M
T
D
P
D
E
V
A
R
Site 56
Y369
K
S
K
P
N
M
N
Y
D
K
L
S
R
A
L
Site 57
Y379
L
S
R
A
L
R
Y
Y
Y
D
K
N
I
M
T
Site 58
Y380
S
R
A
L
R
Y
Y
Y
D
K
N
I
M
T
K
Site 59
Y393
T
K
V
H
G
K
R
Y
A
Y
K
F
D
F
H
Site 60
Y395
V
H
G
K
R
Y
A
Y
K
F
D
F
H
G
I
Site 61
S413
L
Q
P
H
P
P
E
S
S
L
Y
K
Y
P
S
Site 62
S414
Q
P
H
P
P
E
S
S
L
Y
K
Y
P
S
D
Site 63
Y416
H
P
P
E
S
S
L
Y
K
Y
P
S
D
L
P
Site 64
Y418
P
E
S
S
L
Y
K
Y
P
S
D
L
P
Y
M
Site 65
S420
S
S
L
Y
K
Y
P
S
D
L
P
Y
M
G
S
Site 66
Y424
K
Y
P
S
D
L
P
Y
M
G
S
Y
H
A
H
Site 67
S427
S
D
L
P
Y
M
G
S
Y
H
A
H
P
Q
K
Site 68
S462
A
P
N
P
Y
W
N
S
P
T
G
G
I
Y
P
Site 69
Y468
N
S
P
T
G
G
I
Y
P
N
T
R
L
P
T
Site 70
T471
T
G
G
I
Y
P
N
T
R
L
P
T
S
H
M
Site 71
T475
Y
P
N
T
R
L
P
T
S
H
M
P
S
H
L
Site 72
S476
P
N
T
R
L
P
T
S
H
M
P
S
H
L
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation