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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ADH5
Full Name:
Alcohol dehydrogenase class-3
Alias:
ADHX; Alcohol dehydrogenase class 3 chi chain; Alcohol dehydrogenase class-III; EC 1.1.1.1; EC 1.1.1.284; FALDH; FDH; Glutathione dehydrogenase; Glutathione-dependent formaldehyde dehydrogenase; GSH-FDH
Type:
Enzyme, metabolite oxidase
Mass (Da):
39724
Number AA:
374
UniProt ID:
P11766
International Prot ID:
IPI00746777
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0044424
GO:0044464
Uniprot
OncoNet
Molecular Function:
GO:0051903
GO:0004022
GO:0009055
PhosphoSite+
KinaseNET
Biological Process:
GO:0006069
GO:0055114
GO:0051775
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S21
W
E
A
G
K
P
L
S
I
E
E
I
E
V
A
Site 2
Y50
A
V
C
H
T
D
A
Y
T
L
S
G
A
D
P
Site 3
T51
V
C
H
T
D
A
Y
T
L
S
G
A
D
P
E
Site 4
S53
H
T
D
A
Y
T
L
S
G
A
D
P
E
G
C
Site 5
T117
L
C
Q
K
I
R
V
T
Q
G
K
G
L
M
P
Site 6
T127
K
G
L
M
P
D
G
T
S
R
F
T
C
K
G
Site 7
S128
G
L
M
P
D
G
T
S
R
F
T
C
K
G
K
Site 8
T131
P
D
G
T
S
R
F
T
C
K
G
K
T
I
L
Site 9
Y140
K
G
K
T
I
L
H
Y
M
G
T
S
T
F
S
Site 10
T143
T
I
L
H
Y
M
G
T
S
T
F
S
E
Y
T
Site 11
T238
R
A
K
E
F
G
A
T
E
C
I
N
P
Q
D
Site 12
S247
C
I
N
P
Q
D
F
S
K
P
I
Q
E
V
L
Site 13
Y264
M
T
D
G
G
V
D
Y
S
F
E
C
I
G
N
Site 14
T303
A
S
G
E
E
I
A
T
R
P
F
Q
L
V
T
Site 15
T317
T
G
R
T
W
K
G
T
A
F
G
G
W
K
S
Site 16
S324
T
A
F
G
G
W
K
S
V
E
S
V
P
K
L
Site 17
S327
G
G
W
K
S
V
E
S
V
P
K
L
V
S
E
Site 18
S333
E
S
V
P
K
L
V
S
E
Y
M
S
K
K
I
Site 19
S337
K
L
V
S
E
Y
M
S
K
K
I
K
V
D
E
Site 20
S351
E
F
V
T
H
N
L
S
F
D
E
I
N
K
A
Site 21
S364
K
A
F
E
L
M
H
S
G
K
S
I
R
T
V
Site 22
S367
E
L
M
H
S
G
K
S
I
R
T
V
V
K
I
Site 23
T370
H
S
G
K
S
I
R
T
V
V
K
I
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation