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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ANXA3
Full Name:
Annexin A3
Alias:
35-alpha calcimedin; Annexin III; ANX3; Lipocortin III
Type:
Calcium-binding protein
Mass (Da):
36244
Number AA:
332
UniProt ID:
P12429
International Prot ID:
IPI00024095
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0005544
GO:0019834
PhosphoSite+
KinaseNET
Biological Process:
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y15
H
R
G
T
V
R
D
Y
P
D
F
S
P
S
V
Site 2
S19
V
R
D
Y
P
D
F
S
P
S
V
D
A
E
A
Site 3
S21
D
Y
P
D
F
S
P
S
V
D
A
E
A
I
Q
Site 4
T46
K
M
L
I
S
I
L
T
E
R
S
N
A
Q
R
Site 5
Y60
R
Q
L
I
V
K
E
Y
Q
A
A
Y
G
K
E
Site 6
S77
D
D
L
K
G
D
L
S
G
H
F
E
H
L
M
Site 7
S102
D
A
K
Q
L
K
K
S
M
K
G
A
G
T
N
Site 8
T118
D
A
L
I
E
I
L
T
T
R
T
S
R
Q
M
Site 9
T119
A
L
I
E
I
L
T
T
R
T
S
R
Q
M
K
Site 10
S122
E
I
L
T
T
R
T
S
R
Q
M
K
D
I
S
Site 11
Y132
M
K
D
I
S
Q
A
Y
Y
T
V
Y
K
K
S
Site 12
Y133
K
D
I
S
Q
A
Y
Y
T
V
Y
K
K
S
L
Site 13
T134
D
I
S
Q
A
Y
Y
T
V
Y
K
K
S
L
G
Site 14
Y136
S
Q
A
Y
Y
T
V
Y
K
K
S
L
G
D
D
Site 15
S139
Y
Y
T
V
Y
K
K
S
L
G
D
D
I
S
S
Site 16
S145
K
S
L
G
D
D
I
S
S
E
T
S
G
D
F
Site 17
S146
S
L
G
D
D
I
S
S
E
T
S
G
D
F
R
Site 18
S149
D
D
I
S
S
E
T
S
G
D
F
R
K
A
L
Site 19
T158
D
F
R
K
A
L
L
T
L
A
D
G
R
R
D
Site 20
S167
A
D
G
R
R
D
E
S
L
K
V
D
E
H
L
Site 21
Y183
K
Q
D
A
Q
I
L
Y
K
A
G
E
N
R
W
Site 22
T192
A
G
E
N
R
W
G
T
D
E
D
K
F
T
E
Site 23
T198
G
T
D
E
D
K
F
T
E
I
L
C
L
R
S
Site 24
T212
S
F
P
Q
L
K
L
T
F
D
E
Y
R
N
I
Site 25
Y216
L
K
L
T
F
D
E
Y
R
N
I
S
Q
K
D
Site 26
S220
F
D
E
Y
R
N
I
S
Q
K
D
I
V
D
S
Site 27
S227
S
Q
K
D
I
V
D
S
I
K
G
E
L
S
G
Site 28
T267
R
A
L
K
G
I
G
T
D
E
F
T
L
N
R
Site 29
T289
I
D
L
L
D
I
R
T
E
F
K
K
H
Y
G
Site 30
Y295
R
T
E
F
K
K
H
Y
G
Y
S
L
Y
S
A
Site 31
Y297
E
F
K
K
H
Y
G
Y
S
L
Y
S
A
I
K
Site 32
S298
F
K
K
H
Y
G
Y
S
L
Y
S
A
I
K
S
Site 33
Y300
K
H
Y
G
Y
S
L
Y
S
A
I
K
S
D
T
Site 34
S301
H
Y
G
Y
S
L
Y
S
A
I
K
S
D
T
S
Site 35
S305
S
L
Y
S
A
I
K
S
D
T
S
G
D
Y
E
Site 36
S308
S
A
I
K
S
D
T
S
G
D
Y
E
I
T
L
Site 37
Y311
K
S
D
T
S
G
D
Y
E
I
T
L
L
K
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation