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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
BMP2
Full Name:
Bone morphogenetic protein 2
Alias:
Bone morphogenetic protein 2A
Type:
Mass (Da):
44702
Number AA:
396
UniProt ID:
P12643
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S37
R
R
K
F
A
A
A
S
S
G
R
P
S
S
Q
Site 2
S38
R
K
F
A
A
A
S
S
G
R
P
S
S
Q
P
Site 3
S42
A
A
S
S
G
R
P
S
S
Q
P
S
D
E
V
Site 4
S43
A
S
S
G
R
P
S
S
Q
P
S
D
E
V
L
Site 5
S46
G
R
P
S
S
Q
P
S
D
E
V
L
S
E
F
Site 6
S59
E
F
E
L
R
L
L
S
M
F
G
L
K
Q
R
Site 7
T68
F
G
L
K
Q
R
P
T
P
S
R
D
A
V
V
Site 8
S70
L
K
Q
R
P
T
P
S
R
D
A
V
V
P
P
Site 9
Y78
R
D
A
V
V
P
P
Y
M
L
D
L
Y
R
R
Site 10
Y83
P
P
Y
M
L
D
L
Y
R
R
H
S
G
Q
P
Site 11
S87
L
D
L
Y
R
R
H
S
G
Q
P
G
S
P
A
Site 12
S92
R
H
S
G
Q
P
G
S
P
A
P
D
H
R
L
Site 13
S104
H
R
L
E
R
A
A
S
R
A
N
T
V
R
S
Site 14
T108
R
A
A
S
R
A
N
T
V
R
S
F
H
H
E
Site 15
S111
S
R
A
N
T
V
R
S
F
H
H
E
E
S
L
Site 16
S117
R
S
F
H
H
E
E
S
L
E
E
L
P
E
T
Site 17
T124
S
L
E
E
L
P
E
T
S
G
K
T
T
R
R
Site 18
T128
L
P
E
T
S
G
K
T
T
R
R
F
F
F
N
Site 19
T129
P
E
T
S
G
K
T
T
R
R
F
F
F
N
L
Site 20
S137
R
R
F
F
F
N
L
S
S
I
P
T
E
E
F
Site 21
S147
P
T
E
E
F
I
T
S
A
E
L
Q
V
F
R
Site 22
S166
D
A
L
G
N
N
S
S
F
H
H
R
I
N
I
Site 23
Y174
F
H
H
R
I
N
I
Y
E
I
I
K
P
A
T
Site 24
T181
Y
E
I
I
K
P
A
T
A
N
S
K
F
P
V
Site 25
S184
I
K
P
A
T
A
N
S
K
F
P
V
T
R
L
Site 26
S202
R
L
V
N
Q
N
A
S
R
W
E
S
F
D
V
Site 27
S206
Q
N
A
S
R
W
E
S
F
D
V
T
P
A
V
Site 28
S240
L
E
E
K
Q
G
V
S
K
R
H
V
R
I
S
Site 29
S247
S
K
R
H
V
R
I
S
R
S
L
H
Q
D
E
Site 30
S249
R
H
V
R
I
S
R
S
L
H
Q
D
E
H
S
Site 31
S256
S
L
H
Q
D
E
H
S
W
S
Q
I
R
P
L
Site 32
S258
H
Q
D
E
H
S
W
S
Q
I
R
P
L
L
V
Site 33
T266
Q
I
R
P
L
L
V
T
F
G
H
D
G
K
G
Site 34
S294
K
Q
R
K
R
L
K
S
S
C
K
R
H
P
L
Site 35
S295
Q
R
K
R
L
K
S
S
C
K
R
H
P
L
Y
Site 36
Y302
S
C
K
R
H
P
L
Y
V
D
F
S
D
V
G
Site 37
Y385
E
K
V
V
L
K
N
Y
Q
D
M
V
V
E
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation