KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
COX4I1
Full Name:
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial
Alias:
COX IV-1; COX4; COX41; COXIV; Cytochrome c oxidase polypeptide IV; Cytochrome c oxidase subunit IV isoform 1
Type:
Mitochondrial; Energy Metabolism - oxidative phosphorylation; Oxidoreductase; EC 1.9.3.1
Mass (Da):
19577
Number AA:
169
UniProt ID:
P13073
International Prot ID:
IPI00006579
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005743
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0004129
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006091
Phosida
TranscriptoNet
STRING
Kinexus Products
Cytochrome c oxidase subunit 4 pan-specific antibody AB-NN379-1#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NN379-1
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
G
K
R
A
I
S
T
S
V
C
V
R
A
H
E
Site 2
S26
V
C
V
R
A
H
E
S
V
V
K
S
E
D
F
Site 3
S30
A
H
E
S
V
V
K
S
E
D
F
S
L
P
A
Site 4
S34
V
V
K
S
E
D
F
S
L
P
A
Y
M
D
R
Site 5
Y38
E
D
F
S
L
P
A
Y
M
D
R
R
D
H
P
Site 6
S56
V
A
H
V
K
H
L
S
A
S
Q
K
A
L
K
Site 7
S58
H
V
K
H
L
S
A
S
Q
K
A
L
K
E
K
Site 8
S69
L
K
E
K
E
K
A
S
W
S
S
L
S
M
D
Site 9
S72
K
E
K
A
S
W
S
S
L
S
M
D
E
K
V
Site 10
S74
K
A
S
W
S
S
L
S
M
D
E
K
V
E
L
Site 11
Y82
M
D
E
K
V
E
L
Y
R
I
K
F
K
E
S
Site 12
S89
Y
R
I
K
F
K
E
S
F
A
E
M
N
R
G
Site 13
T102
R
G
S
N
E
W
K
T
V
V
G
G
A
M
F
Site 14
Y124
V
I
M
W
Q
K
H
Y
V
Y
G
P
L
P
Q
Site 15
S132
V
Y
G
P
L
P
Q
S
F
D
K
E
W
V
A
Site 16
S158
N
P
I
Q
G
L
A
S
K
W
D
Y
E
K
N
Site 17
Y162
G
L
A
S
K
W
D
Y
E
K
N
E
W
K
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation