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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Hoxd8
Full Name:
Homeobox protein Hox-D8
Alias:
Homeobox d8; Hox4; Hox4e; Hox5.4
Type:
Nucleus protein
Mass (Da):
31911
Number AA:
290
UniProt ID:
P13378
International Prot ID:
IPI00008481
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0043565
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0008595
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y10
S
Y
F
V
N
P
L
Y
S
K
Y
K
A
A
A
Site 2
S11
Y
F
V
N
P
L
Y
S
K
Y
K
A
A
A
A
Site 3
Y13
V
N
P
L
Y
S
K
Y
K
A
A
A
A
A
A
Site 4
Y31
G
E
A
I
N
P
T
Y
Y
D
C
H
F
A
P
Site 5
Y32
E
A
I
N
P
T
Y
Y
D
C
H
F
A
P
E
Site 6
S75
A
H
A
H
P
H
P
S
P
P
P
S
G
T
G
Site 7
S79
P
H
P
S
P
P
P
S
G
T
G
C
G
G
R
Site 8
T81
P
S
P
P
P
S
G
T
G
C
G
G
R
E
G
Site 9
Y93
R
E
G
R
G
Q
E
Y
F
H
P
G
G
G
S
Site 10
S100
Y
F
H
P
G
G
G
S
P
A
A
A
Y
Q
A
Site 11
Y105
G
G
S
P
A
A
A
Y
Q
A
A
P
P
P
P
Site 12
Y137
H
G
E
P
A
K
F
Y
G
Y
D
N
L
Q
R
Site 13
T149
L
Q
R
Q
P
I
F
T
T
Q
Q
E
A
E
L
Site 14
Y159
Q
E
A
E
L
V
Q
Y
P
D
C
K
S
S
S
Site 15
S164
V
Q
Y
P
D
C
K
S
S
S
G
N
I
G
E
Site 16
S166
Y
P
D
C
K
S
S
S
G
N
I
G
E
D
P
Site 17
S179
D
P
D
H
L
N
Q
S
S
S
P
S
Q
M
F
Site 18
S181
D
H
L
N
Q
S
S
S
P
S
Q
M
F
P
W
Site 19
S183
L
N
Q
S
S
S
P
S
Q
M
F
P
W
M
R
Site 20
T203
G
R
R
R
G
R
Q
T
Y
S
R
F
Q
T
L
Site 21
Y204
R
R
R
G
R
Q
T
Y
S
R
F
Q
T
L
E
Site 22
S205
R
R
G
R
Q
T
Y
S
R
F
Q
T
L
E
L
Site 23
T209
Q
T
Y
S
R
F
Q
T
L
E
L
E
K
E
F
Site 24
Y221
K
E
F
L
F
N
P
Y
L
T
R
K
R
R
I
Site 25
S231
R
K
R
R
I
E
V
S
H
A
L
A
L
T
E
Site 26
S264
N
K
D
K
F
P
V
S
R
Q
E
V
K
D
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation