PhosphoNET

           
Protein Info 
   
Short Name:  ATP1A3
Full Name:  Sodium/potassium-transporting ATPase subunit alpha-3
Alias:  AT1A3; ATPase, Na+/K+ transporting, alpha 3 polypeptide; DYT12; EC 3.6.3.9; Na(+)/K(+) ATPase alpha(III); Na(+)/K(+) ATPase alpha(III) subunit; Sodium pump alpha-3; Sodium pump subunit alpha-3; Sodium/potassium-transporting ATPase alpha-3
Type:  Plasma membrane, Cytoplasm, Endoplasmic reticulum, Nucleus, Sodium:potassium-exchanging ATPase complex, Golgi apparatus, Integral membrane protein
Mass (Da):  111749
Number AA:  1013
UniProt ID:  P13637
International Prot ID:  IPI00302840
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005794  GO:0005783  GO:0005890 Uniprot OncoNet
Molecular Function:  GO:0005524  GO:0000287  GO:0015077 PhosphoSite+ KinaseNET
Biological Process:  GO:0006754  GO:0006813  GO:0006814 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S10DKKDDKDSPKKNKGK
Site 2T32LKKEVAMTEHKMSVE
Site 3S37AMTEHKMSVEEVCRK
Site 4Y45VEEVCRKYNTDCVQG
Site 5T71RDGPNALTPPPTTPE
Site 6T75NALTPPPTTPEWVKF
Site 7T76ALTPPPTTPEWVKFC
Site 8S116AGTEDDPSGDNLYLG
Site 9Y139ITGCFSYYQEAKSSK
Site 10S144SYYQEAKSSKIMESF
Site 11S145YYQEAKSSKIMESFK
Site 12S150KSSKIMESFKNMVPQ
Site 13S206HGCKVDNSSLTGESE
Site 14S207GCKVDNSSLTGESEP
Site 15T209KVDNSSLTGESEPQT
Site 16S212NSSLTGESEPQTRSP
Site 17T216TGESEPQTRSPDCTH
Site 18S218ESEPQTRSPDCTHDN
Site 19T222QTRSPDCTHDNPLET
Site 20T233PLETRNITFFSTNCV
Site 21T237RNITFFSTNCVEGTA
Site 22S265GRIATLASGLEVGKT
Site 23T356KNLEAVETLGSTSTI
Site 24S359EAVETLGSTSTICSD
Site 25T360AVETLGSTSTICSDK
Site 26S361VETLGSTSTICSDKT
Site 27T362ETLGSTSTICSDKTG
Site 28S365GSTSTICSDKTGTLT
Site 29T368STICSDKTGTLTQNR
Site 30T372SDKTGTLTQNRMTVA
Site 31T392NQIHEADTTEDQSGT
Site 32T393QIHEADTTEDQSGTS
Site 33S397ADTTEDQSGTSFDKS
Site 34S400TEDQSGTSFDKSSHT
Site 35S404SGTSFDKSSHTWVAL
Site 36S405GTSFDKSSHTWVALS
Site 37T407SFDKSSHTWVALSHI
Site 38S442RDVAGDASESALLKC
Site 39S453LLKCIELSSGSVKLM
Site 40S454LKCIELSSGSVKLMR
Site 41S456CIELSSGSVKLMRER
Site 42S474VAEIPFNSTNKYQLS
Site 43T475AEIPFNSTNKYQLSI
Site 44Y478PFNSTNKYQLSIHET
Site 45S481STNKYQLSIHETEDP
Site 46T485YQLSIHETEDPNDNR
Site 47Y493EDPNDNRYLLVMKGA
Site 48S509ERILDRCSTILLQGK
Site 49T510RILDRCSTILLQGKE
Site 50Y532KEAFQNAYLELGGLG
Site 51Y548RVLGFCHYYLPEEQF
Site 52Y549VLGFCHYYLPEEQFP
Site 53S625AKGVGIISEGNETVE
Site 54T630IISEGNETVEDIAAR
Site 55S643ARLNIPVSQVNPRDA
Site 56T664GTDLKDFTSEQIDEI
Site 57S665TDLKDFTSEQIDEIL
Site 58S712TGDGVNDSPALKKAD
Site 59S765IFDNLKKSIAYTLTS
Site 60T769LKKSIAYTLTSNIPE
Site 61S819LAYEAAESDIMKRQP
Site 62T831RQPRNPRTDKLVNER
Site 63T884RLNWDDRTVNDLEDS
Site 64Y892VNDLEDSYGQQWTYE
Site 65Y898SYGQQWTYEQRKVVE
Site 66T929ADLIICKTRRNSVFQ
Site 67S933ICKTRRNSVFQQGMK
Site 68T1011GGWVEKETYY_____
Site 69Y1012GWVEKETYY      
Site 70Y1013WVEKETYY       
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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