KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ACP5
Full Name:
Tartrate-resistant acid phosphatase type 5
Alias:
Acid phosphatase 5, tartrate resistant; EC 3.1.3.2; PPA5; Tartrate resistant; Tartrate-resistant acid ATPase; Tartrate-resistant acid phosphatase type 5; TRAP; TR-AP; TrATPas; TrATPase
Type:
Phosphatase (non-protein); Cofactor and Vitamin Metabolism - riboflavin; EC 3.1.3.2
Mass (Da):
36599
Number AA:
325
UniProt ID:
P13686
International Prot ID:
IPI00419240
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
GO:0016021
GO:0005764
Uniprot
OncoNet
Molecular Function:
GO:0003993
GO:0005506
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T57
N
A
K
E
I
A
R
T
V
Q
I
L
G
A
D
Site 2
T89
N
D
K
R
F
Q
E
T
F
E
D
V
F
S
D
Site 3
S95
E
T
F
E
D
V
F
S
D
R
S
L
R
K
V
Site 4
S98
E
D
V
F
S
D
R
S
L
R
K
V
P
W
Y
Site 5
Y105
S
L
R
K
V
P
W
Y
V
L
A
G
N
H
D
Site 6
S124
V
S
A
Q
I
A
Y
S
K
I
S
K
R
W
N
Site 7
Y137
W
N
F
P
S
P
F
Y
R
L
H
F
K
I
P
Site 8
S164
T
V
T
L
C
G
N
S
D
D
F
L
S
Q
Q
Site 9
S169
G
N
S
D
D
F
L
S
Q
Q
P
E
R
P
R
Site 10
Y199
L
A
A
A
R
E
D
Y
V
L
V
A
G
H
Y
Site 11
Y206
Y
V
L
V
A
G
H
Y
P
V
W
S
I
A
E
Site 12
T217
S
I
A
E
H
G
P
T
H
C
L
V
K
Q
L
Site 13
Y236
A
T
Y
G
V
T
A
Y
L
C
G
H
D
H
N
Site 14
Y246
G
H
D
H
N
L
Q
Y
L
Q
D
E
N
G
V
Site 15
Y255
Q
D
E
N
G
V
G
Y
V
L
S
G
A
G
N
Site 16
S267
A
G
N
F
M
D
P
S
K
R
H
Q
R
K
V
Site 17
Y278
Q
R
K
V
P
N
G
Y
L
R
F
H
Y
G
T
Site 18
Y283
N
G
Y
L
R
F
H
Y
G
T
E
D
S
L
G
Site 19
T285
Y
L
R
F
H
Y
G
T
E
D
S
L
G
G
F
Site 20
S288
F
H
Y
G
T
E
D
S
L
G
G
F
A
Y
V
Site 21
Y294
D
S
L
G
G
F
A
Y
V
E
I
S
S
K
E
Site 22
T303
E
I
S
S
K
E
M
T
V
T
Y
I
E
A
S
Site 23
T305
S
S
K
E
M
T
V
T
Y
I
E
A
S
G
K
Site 24
Y306
S
K
E
M
T
V
T
Y
I
E
A
S
G
K
S
Site 25
S313
Y
I
E
A
S
G
K
S
L
F
K
T
R
L
P
Site 26
T317
S
G
K
S
L
F
K
T
R
L
P
R
R
A
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation