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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TPT1
Full Name:
Translationally-controlled tumor protein
Alias:
Fortilin; Histamine-releasing factor; HRF; TCTP; Translationally-controlled tumor protein; Tumor protein, translationally-controlled 1
Type:
Secreted protein, microtubule-binding protein
Mass (Da):
19595
Number AA:
172
UniProt ID:
P13693
International Prot ID:
IPI00550900
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005615
GO:0005771
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006916
GO:0006816
GO:0006874
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
I
S
H
D
E
M
F
S
D
I
Y
K
I
R
E
Site 2
Y18
D
E
M
F
S
D
I
Y
K
I
R
E
I
A
D
Site 3
S37
E
V
E
G
K
M
V
S
R
T
E
G
N
I
D
Site 4
T39
E
G
K
M
V
S
R
T
E
G
N
I
D
D
S
Site 5
S46
T
E
G
N
I
D
D
S
L
I
G
G
N
A
S
Site 6
S53
S
L
I
G
G
N
A
S
A
E
G
P
E
G
E
Site 7
T62
E
G
P
E
G
E
G
T
E
S
T
V
I
T
G
Site 8
S64
P
E
G
E
G
T
E
S
T
V
I
T
G
V
D
Site 9
T65
E
G
E
G
T
E
S
T
V
I
T
G
V
D
I
Site 10
S82
N
H
H
L
Q
E
T
S
F
T
K
E
A
Y
K
Site 11
T84
H
L
Q
E
T
S
F
T
K
E
A
Y
K
K
Y
Site 12
Y88
T
S
F
T
K
E
A
Y
K
K
Y
I
K
D
Y
Site 13
Y91
T
K
E
A
Y
K
K
Y
I
K
D
Y
M
K
S
Site 14
Y95
Y
K
K
Y
I
K
D
Y
M
K
S
I
K
G
K
Site 15
S98
Y
I
K
D
Y
M
K
S
I
K
G
K
L
E
E
Site 16
T116
E
R
V
K
P
F
M
T
G
A
A
E
Q
I
K
Site 17
Y132
I
L
A
N
F
K
N
Y
Q
F
F
I
G
E
N
Site 18
Y151
G
M
V
A
L
L
D
Y
R
E
D
G
V
T
P
Site 19
T157
D
Y
R
E
D
G
V
T
P
Y
M
I
F
F
K
Site 20
Y159
R
E
D
G
V
T
P
Y
M
I
F
F
K
D
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation