PhosphoNET

           
Protein Info 
   
Short Name:  OSM
Full Name:  Oncostatin-M
Alias:  ONCM; oncostatin M
Type:  Cytokine
Mass (Da):  28484
Number AA:  252
UniProt ID:  P13725
International Prot ID:  IPI00010336
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005615  GO:0005900   Uniprot OncoNet
Molecular Function:  GO:0005125  GO:0008083  GO:0005147 PhosphoSite+ KinaseNET
Biological Process:  GO:0008283  GO:0006955  GO:0008285 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S30ASMAAIGSCSKEYRV
Site 2T52QTDLMQDTSRLLDPY
Site 3S53TDLMQDTSRLLDPYI
Site 4Y59TSRLLDPYIRIQGLD
Site 5S83ERPGAFPSEETLRGL
Site 6T86GAFPSEETLRGLGRR
Site 7T98GRRGFLQTLNATLGC
Site 8T102FLQTLNATLGCVLHR
Site 9S160MAQLLDNSDTAEPTK
Site 10T162QLLDNSDTAEPTKAG
Site 11S173TKAGRGASQPPTPTP
Site 12T177RGASQPPTPTPASDA
Site 13T179ASQPPTPTPASDAFQ
Site 14S182PPTPTPASDAFQRKL
Site 15S210HSVGRVFSKWGESPN
Site 16S215VFSKWGESPNRSRRH
Site 17S219WGESPNRSRRHSPHQ
Site 18S223PNRSRRHSPHQALRK
Site 19T235LRKGVRRTRPSRKGK
Site 20S238GVRRTRPSRKGKRLM
Site 21T246RKGKRLMTRGQLPR_
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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