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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LCP1
Full Name:
Plastin-2
Alias:
CP64; LC64P; LCP-1; LPL; L-PLASTIN; L-plastin; Lymphocyte cytosolic protein 1; Plastin, L; Plastin-2; PLS2; PLSL
Type:
Actin binding protein
Mass (Da):
70289
Number AA:
627
UniProt ID:
P13796
International Prot ID:
IPI00010471
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030054
GO:0005829
GO:0001891
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0042802
PhosphoSite+
KinaseNET
Biological Process:
GO:0002286
GO:0033157
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
A
R
G
S
V
S
D
E
E
M
M
Site 2
S7
_
M
A
R
G
S
V
S
D
E
E
M
M
E
L
Site 3
T23
E
A
F
A
K
V
D
T
D
G
N
G
Y
I
S
Site 4
Y28
V
D
T
D
G
N
G
Y
I
S
F
N
E
L
N
Site 5
S30
T
D
G
N
G
Y
I
S
F
N
E
L
N
D
L
Site 6
Y48
A
C
L
P
L
P
G
Y
R
V
R
E
I
T
E
Site 7
T54
G
Y
R
V
R
E
I
T
E
N
L
M
A
T
G
Site 8
S70
L
D
Q
D
G
R
I
S
F
D
E
F
I
K
I
Site 9
S83
K
I
F
H
G
L
K
S
T
D
V
A
K
T
F
Site 10
T89
K
S
T
D
V
A
K
T
F
R
K
A
I
N
K
Site 11
S110
I
G
G
T
S
E
Q
S
S
V
G
T
Q
H
S
Site 12
S111
G
G
T
S
E
Q
S
S
V
G
T
Q
H
S
Y
Site 13
T114
S
E
Q
S
S
V
G
T
Q
H
S
Y
S
E
E
Site 14
S117
S
S
V
G
T
Q
H
S
Y
S
E
E
E
K
Y
Site 15
Y118
S
V
G
T
Q
H
S
Y
S
E
E
E
K
Y
A
Site 16
S119
V
G
T
Q
H
S
Y
S
E
E
E
K
Y
A
F
Site 17
Y124
S
Y
S
E
E
E
K
Y
A
F
V
N
W
I
N
Site 18
T174
I
N
L
S
V
P
D
T
I
D
E
R
T
I
N
Site 19
T186
T
I
N
K
K
K
L
T
P
F
T
I
Q
E
N
Site 20
Y222
D
L
K
E
G
K
P
Y
L
V
L
G
L
L
W
Site 21
S243
L
F
A
D
I
E
L
S
R
N
E
A
L
I
A
Site 22
S257
A
L
L
R
E
G
E
S
L
E
D
L
M
K
L
Site 23
S265
L
E
D
L
M
K
L
S
P
E
E
L
L
L
R
Site 24
Y276
L
L
L
R
W
A
N
Y
H
L
E
N
A
G
C
Site 25
T291
N
K
I
G
N
F
S
T
D
I
K
D
S
K
A
Site 26
Y299
D
I
K
D
S
K
A
Y
Y
H
L
L
E
Q
V
Site 27
Y300
I
K
D
S
K
A
Y
Y
H
L
L
E
Q
V
A
Site 28
S323
P
A
V
V
I
D
M
S
G
L
R
E
K
D
D
Site 29
T351
L
G
C
R
Q
F
V
T
A
T
D
V
V
R
G
Site 30
T353
C
R
Q
F
V
T
A
T
D
V
V
R
G
N
P
Site 31
Y374
I
A
N
L
F
N
R
Y
P
A
L
H
K
P
E
Site 32
T399
G
E
T
R
E
E
R
T
F
R
N
W
M
N
S
Site 33
Y417
N
P
R
V
N
H
L
Y
S
D
L
S
D
A
L
Site 34
S421
N
H
L
Y
S
D
L
S
D
A
L
V
I
F
Q
Site 35
Y430
A
L
V
I
F
Q
L
Y
E
K
I
K
V
P
V
Site 36
Y447
N
R
V
N
K
P
P
Y
P
K
L
G
G
N
M
Site 37
Y462
K
K
L
E
N
C
N
Y
A
V
E
L
G
K
N
Site 38
S474
G
K
N
Q
A
K
F
S
L
V
G
I
G
G
Q
Site 39
T489
D
L
N
E
G
N
R
T
L
T
L
A
L
I
W
Site 40
T491
N
E
G
N
R
T
L
T
L
A
L
I
W
Q
L
Site 41
Y502
I
W
Q
L
M
R
R
Y
T
L
N
I
L
E
E
Site 42
T503
W
Q
L
M
R
R
Y
T
L
N
I
L
E
E
I
Site 43
S535
T
L
R
E
A
E
K
S
S
S
I
S
S
F
K
Site 44
S536
L
R
E
A
E
K
S
S
S
I
S
S
F
K
D
Site 45
S537
R
E
A
E
K
S
S
S
I
S
S
F
K
D
P
Site 46
S539
A
E
K
S
S
S
I
S
S
F
K
D
P
K
I
Site 47
S540
E
K
S
S
S
I
S
S
F
K
D
P
K
I
S
Site 48
S547
S
F
K
D
P
K
I
S
T
S
L
P
V
L
D
Site 49
S563
I
D
A
I
Q
P
G
S
I
N
Y
D
L
L
K
Site 50
Y585
E
K
L
N
N
A
K
Y
A
I
S
M
A
R
K
Site 51
S588
N
N
A
K
Y
A
I
S
M
A
R
K
I
G
A
Site 52
Y598
R
K
I
G
A
R
V
Y
A
L
P
E
D
L
V
Site 53
T614
V
N
P
K
M
V
M
T
V
F
A
C
L
M
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation