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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ANXA8
Full Name:
Annexin A8
Alias:
Annexin VIII; Annexin-8; ANX8; VAC-beta; Vascular anticoagulant-beta
Type:
Mass (Da):
36880
Number AA:
UniProt ID:
P13928
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0005544
PhosphoSite+
KinaseNET
Biological Process:
GO:0007596
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T14
W
I
E
Q
E
G
V
T
V
K
S
S
S
H
F
Site 2
S17
Q
E
G
V
T
V
K
S
S
S
H
F
N
P
D
Site 3
S19
G
V
T
V
K
S
S
S
H
F
N
P
D
P
D
Site 4
T29
N
P
D
P
D
A
E
T
L
Y
K
A
M
K
G
Site 5
Y31
D
P
D
A
E
T
L
Y
K
A
M
K
G
I
G
Site 6
T49
Q
A
I
I
D
V
L
T
K
R
S
N
T
Q
R
Site 7
T54
V
L
T
K
R
S
N
T
Q
R
Q
Q
I
A
K
Site 8
S62
Q
R
Q
Q
I
A
K
S
F
K
A
Q
F
G
K
Site 9
T72
A
Q
F
G
K
D
L
T
E
T
L
K
S
E
L
Site 10
T74
F
G
K
D
L
T
E
T
L
K
S
E
L
S
G
Site 11
S77
D
L
T
E
T
L
K
S
E
L
S
G
K
F
E
Site 12
S80
E
T
L
K
S
E
L
S
G
K
F
E
R
L
I
Site 13
Y95
V
A
L
M
Y
P
P
Y
R
Y
E
A
K
E
L
Site 14
Y97
L
M
Y
P
P
Y
R
Y
E
A
K
E
L
H
D
Site 15
Y135
L
R
E
I
M
K
A
Y
E
E
D
Y
G
S
S
Site 16
Y139
M
K
A
Y
E
E
D
Y
G
S
S
L
E
E
D
Site 17
S141
A
Y
E
E
D
Y
G
S
S
L
E
E
D
I
Q
Site 18
S152
E
D
I
Q
A
D
T
S
G
Y
L
E
R
I
L
Site 19
S171
Q
G
S
R
D
D
V
S
S
F
V
D
P
G
L
Site 20
S172
G
S
R
D
D
V
S
S
F
V
D
P
G
L
A
Site 21
Y187
L
Q
D
A
Q
D
L
Y
A
A
G
E
K
I
R
Site 22
T196
A
G
E
K
I
R
G
T
D
E
M
K
F
I
T
Site 23
Y220
L
L
R
V
F
E
E
Y
E
K
I
A
N
K
S
Site 24
S227
Y
E
K
I
A
N
K
S
I
E
D
S
I
K
S
Site 25
S231
A
N
K
S
I
E
D
S
I
K
S
E
T
H
G
Site 26
S234
S
I
E
D
S
I
K
S
E
T
H
G
S
L
E
Site 27
S239
I
K
S
E
T
H
G
S
L
E
E
A
M
L
T
Site 28
Y257
C
T
Q
N
L
H
S
Y
F
A
E
R
L
Y
Y
Site 29
Y263
S
Y
F
A
E
R
L
Y
Y
A
M
K
G
A
G
Site 30
Y264
Y
F
A
E
R
L
Y
Y
A
M
K
G
A
G
T
Site 31
T271
Y
A
M
K
G
A
G
T
R
D
G
T
L
I
R
Site 32
T275
G
A
G
T
R
D
G
T
L
I
R
N
I
V
S
Site 33
Y299
K
C
H
F
K
K
M
Y
G
K
T
L
S
S
M
Site 34
T302
F
K
K
M
Y
G
K
T
L
S
S
M
I
M
E
Site 35
S304
K
M
Y
G
K
T
L
S
S
M
I
M
E
D
T
Site 36
S312
S
M
I
M
E
D
T
S
G
D
Y
K
N
A
L
Site 37
Y315
M
E
D
T
S
G
D
Y
K
N
A
L
L
S
L
Site 38
S321
D
Y
K
N
A
L
L
S
L
V
G
S
D
P
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation