KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ENO3
Full Name:
Beta-enolase
Alias:
2-phospho-D-glycerate hydro-lyase
Type:
Enzyme, cellular metabolism
Mass (Da):
46932
Number AA:
434
UniProt ID:
P13929
International Prot ID:
IPI00218474
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000015
GO:0005737
GO:0032991
Uniprot
OncoNet
Molecular Function:
GO:0000287
GO:0003824
GO:0004634
PhosphoSite+
KinaseNET
Biological Process:
GO:0005975
GO:0005996
GO:0006006
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
F
A
R
E
I
L
D
S
R
G
N
P
T
V
E
Site 2
T19
L
D
S
R
G
N
P
T
V
E
V
D
L
H
T
Site 3
S37
R
F
R
A
A
V
P
S
G
A
S
T
G
I
Y
Site 4
S40
A
A
V
P
S
G
A
S
T
G
I
Y
E
A
L
Site 5
T41
A
V
P
S
G
A
S
T
G
I
Y
E
A
L
E
Site 6
Y44
S
G
A
S
T
G
I
Y
E
A
L
E
L
R
D
Site 7
Y57
R
D
G
D
K
G
R
Y
L
G
K
G
V
L
K
Site 8
S83
A
L
L
Q
K
K
L
S
V
A
D
Q
E
K
V
Site 9
T100
F
M
I
E
L
D
G
T
E
N
K
S
K
F
G
Site 10
S104
L
D
G
T
E
N
K
S
K
F
G
A
N
A
I
Site 11
Y131
A
E
K
G
V
P
L
Y
R
H
I
A
D
L
A
Site 12
S176
M
I
L
P
V
G
A
S
S
F
K
E
A
M
R
Site 13
Y189
M
R
I
G
A
E
V
Y
H
H
L
K
G
V
I
Site 14
Y200
K
G
V
I
K
A
K
Y
G
K
D
A
T
N
V
Site 15
T205
A
K
Y
G
K
D
A
T
N
V
G
D
E
G
G
Site 16
Y236
T
A
I
Q
A
A
G
Y
P
D
K
V
V
I
G
Site 17
S249
I
G
M
D
V
A
A
S
E
F
Y
R
N
G
K
Site 18
Y257
E
F
Y
R
N
G
K
Y
D
L
D
F
K
S
P
Site 19
S263
K
Y
D
L
D
F
K
S
P
D
D
P
A
R
H
Site 20
T272
D
D
P
A
R
H
I
T
G
E
K
L
G
E
L
Site 21
Y280
G
E
K
L
G
E
L
Y
K
S
F
I
K
N
Y
Site 22
S282
K
L
G
E
L
Y
K
S
F
I
K
N
Y
P
V
Site 23
Y287
Y
K
S
F
I
K
N
Y
P
V
V
S
I
E
D
Site 24
T321
Q
I
V
G
D
D
L
T
V
T
N
P
K
R
I
Site 25
T323
V
G
D
D
L
T
V
T
N
P
K
R
I
A
Q
Site 26
S362
Q
A
C
K
L
A
Q
S
N
G
W
G
V
M
V
Site 27
S370
N
G
W
G
V
M
V
S
H
R
S
G
E
T
E
Site 28
T379
R
S
G
E
T
E
D
T
F
I
A
D
L
V
V
Site 29
T390
D
L
V
V
G
L
C
T
G
Q
I
K
T
G
A
Site 30
T395
L
C
T
G
Q
I
K
T
G
A
P
C
R
S
E
Site 31
S401
K
T
G
A
P
C
R
S
E
R
L
A
K
Y
N
Site 32
Y407
R
S
E
R
L
A
K
Y
N
Q
L
M
R
I
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation