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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HGF
Full Name:
Hepatocyte growth factor
Alias:
Hepatopoeitin-A;Scatter factor
Type:
Mass (Da):
83134
Number AA:
728
UniProt ID:
P14210
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T38
G
Q
R
K
R
R
N
T
I
H
E
F
K
K
S
Site 2
S45
T
I
H
E
F
K
K
S
A
K
T
T
L
I
K
Site 3
T48
E
F
K
K
S
A
K
T
T
L
I
K
I
D
P
Site 4
T83
R
N
K
G
L
P
F
T
C
K
A
F
V
F
D
Site 5
S105
W
F
P
F
N
S
M
S
S
G
V
K
K
E
F
Site 6
Y119
F
G
H
E
F
D
L
Y
E
N
K
D
Y
I
R
Site 7
Y124
D
L
Y
E
N
K
D
Y
I
R
N
C
I
I
G
Site 8
Y136
I
I
G
K
G
R
S
Y
K
G
T
V
S
I
T
Site 9
T139
K
G
R
S
Y
K
G
T
V
S
I
T
K
S
G
Site 10
S141
R
S
Y
K
G
T
V
S
I
T
K
S
G
I
K
Site 11
S145
G
T
V
S
I
T
K
S
G
I
K
C
Q
P
W
Site 12
S161
S
M
I
P
H
E
H
S
F
L
P
S
S
Y
R
Site 13
S165
H
E
H
S
F
L
P
S
S
Y
R
G
K
D
L
Site 14
S166
E
H
S
F
L
P
S
S
Y
R
G
K
D
L
Q
Site 15
Y176
G
K
D
L
Q
E
N
Y
C
R
N
P
R
G
E
Site 16
T226
Y
R
G
L
M
D
H
T
E
S
G
K
I
C
Q
Site 17
Y250
H
K
F
L
P
E
R
Y
P
D
K
G
F
D
D
Site 18
Y259
D
K
G
F
D
D
N
Y
C
R
N
P
D
G
Q
Site 19
T296
A
D
N
T
M
N
D
T
D
V
P
L
E
T
T
Site 20
T340
Y
P
H
E
H
D
M
T
P
E
N
F
K
C
K
Site 21
Y353
C
K
D
L
R
E
N
Y
C
R
N
P
D
G
S
Site 22
S362
R
N
P
D
G
S
E
S
P
W
C
F
T
T
D
Site 23
Y376
D
P
N
I
R
V
G
Y
C
S
Q
I
P
N
C
Site 24
Y392
M
S
H
G
Q
D
C
Y
R
G
N
G
K
N
Y
Site 25
Y399
Y
R
G
N
G
K
N
Y
M
G
N
L
S
Q
T
Site 26
S404
K
N
Y
M
G
N
L
S
Q
T
R
S
G
L
T
Site 27
S408
G
N
L
S
Q
T
R
S
G
L
T
C
S
M
W
Site 28
Y439
A
S
K
L
N
E
N
Y
C
R
N
P
D
D
D
Site 29
T473
I
S
R
C
E
G
D
T
T
P
T
I
V
N
L
Site 30
T474
S
R
C
E
G
D
T
T
P
T
I
V
N
L
D
Site 31
S486
N
L
D
H
P
V
I
S
C
A
K
T
K
Q
L
Site 32
T531
I
K
E
S
W
V
L
T
A
R
Q
C
F
P
S
Site 33
S538
T
A
R
Q
C
F
P
S
R
D
L
K
D
Y
E
Site 34
Y544
P
S
R
D
L
K
D
Y
E
A
W
L
G
I
H
Site 35
S568
C
K
Q
V
L
N
V
S
Q
L
V
Y
G
P
E
Site 36
Y572
L
N
V
S
Q
L
V
Y
G
P
E
G
S
D
L
Site 37
Y602
S
T
I
D
L
P
N
Y
G
C
T
I
P
E
K
Site 38
T610
G
C
T
I
P
E
K
T
S
C
S
V
Y
G
W
Site 39
Y615
E
K
T
S
C
S
V
Y
G
W
G
Y
T
G
L
Site 40
T651
Q
H
H
R
G
K
V
T
L
N
E
S
E
I
C
Site 41
S666
A
G
A
E
K
I
G
S
G
P
C
E
G
D
Y
Site 42
Y673
S
G
P
C
E
G
D
Y
G
G
P
L
V
C
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation