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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CPM
Full Name:
Carboxypeptidase M
Alias:
Type:
Mass (Da):
50514
Number AA:
443
UniProt ID:
P14384
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y22
V
A
A
L
D
F
N
Y
H
R
Q
E
G
M
E
Site 2
T34
G
M
E
A
F
L
K
T
V
A
Q
N
Y
S
S
Site 3
S40
K
T
V
A
Q
N
Y
S
S
V
T
H
L
H
S
Site 4
S41
T
V
A
Q
N
Y
S
S
V
T
H
L
H
S
I
Site 5
S47
S
S
V
T
H
L
H
S
I
G
K
S
V
K
G
Site 6
S51
H
L
H
S
I
G
K
S
V
K
G
R
N
L
W
Site 7
Y78
I
G
I
P
E
F
K
Y
V
A
N
M
H
G
D
Site 8
T87
A
N
M
H
G
D
E
T
V
G
R
E
L
L
L
Site 9
S103
L
I
D
Y
L
V
T
S
D
G
K
D
P
E
I
Site 10
Y139
A
V
K
K
P
D
C
Y
Y
S
I
G
R
E
N
Site 11
Y140
V
K
K
P
D
C
Y
Y
S
I
G
R
E
N
Y
Site 12
Y147
Y
S
I
G
R
E
N
Y
N
Q
Y
D
L
N
R
Site 13
Y150
G
R
E
N
Y
N
Q
Y
D
L
N
R
N
F
P
Site 14
Y162
N
F
P
D
A
F
E
Y
N
N
V
S
R
Q
P
Site 15
T171
N
V
S
R
Q
P
E
T
V
A
V
M
K
W
L
Site 16
S186
K
T
E
T
F
V
L
S
A
N
L
H
G
G
A
Site 17
Y211
V
Q
A
T
G
A
L
Y
S
R
S
L
T
P
D
Site 18
S212
Q
A
T
G
A
L
Y
S
R
S
L
T
P
D
D
Site 19
S214
T
G
A
L
Y
S
R
S
L
T
P
D
D
D
V
Site 20
T216
A
L
Y
S
R
S
L
T
P
D
D
D
V
F
Q
Site 21
Y224
P
D
D
D
V
F
Q
Y
L
A
H
T
Y
A
S
Site 22
Y229
F
Q
Y
L
A
H
T
Y
A
S
R
N
P
N
M
Site 23
Y259
V
T
N
G
Y
S
W
Y
P
L
Q
G
G
M
Q
Site 24
S283
F
E
I
T
L
E
L
S
C
C
K
Y
P
R
E
Site 25
Y287
L
E
L
S
C
C
K
Y
P
R
E
E
K
L
P
Site 26
S295
P
R
E
E
K
L
P
S
F
W
N
N
N
K
A
Site 27
Y307
N
K
A
S
L
I
E
Y
I
K
Q
V
H
L
G
Site 28
Y348
C
P
Y
R
T
N
K
Y
G
E
Y
Y
L
L
L
Site 29
Y352
T
N
K
Y
G
E
Y
Y
L
L
L
L
P
G
S
Site 30
T365
G
S
Y
I
I
N
V
T
V
P
G
H
D
P
H
Site 31
T374
P
G
H
D
P
H
I
T
K
V
I
I
P
E
K
Site 32
S382
K
V
I
I
P
E
K
S
Q
N
F
S
A
L
K
Site 33
S386
P
E
K
S
Q
N
F
S
A
L
K
K
D
I
L
Site 34
S402
P
F
Q
G
Q
L
D
S
I
P
V
S
N
P
S
Site 35
Y416
S
C
P
M
I
P
L
Y
R
N
L
P
D
H
S
Site 36
S423
Y
R
N
L
P
D
H
S
A
A
T
K
P
S
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation