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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DRD2
Full Name:
D(2) dopamine receptor
Alias:
Dopamine D2 receptor; dopamine receptor D2
Type:
Receptor, GPCR
Mass (Da):
50619
Number AA:
443
UniProt ID:
P14416
International Prot ID:
IPI00026590
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030424
GO:0030425
GO:0005887
Uniprot
OncoNet
Molecular Function:
GO:0001670
GO:0001591
GO:0008144
PhosphoSite+
KinaseNET
Biological Process:
GO:0060158
GO:0021984
GO:0007628
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y9
D
P
L
N
L
S
W
Y
D
D
D
L
E
R
Q
Site 2
S25
W
S
R
P
F
N
G
S
D
G
K
A
D
R
P
Site 3
Y34
G
K
A
D
R
P
H
Y
N
Y
Y
A
T
L
L
Site 4
Y36
A
D
R
P
H
Y
N
Y
Y
A
T
L
L
T
L
Site 5
Y37
D
R
P
H
Y
N
Y
Y
A
T
L
L
T
L
L
Site 6
T134
A
I
S
I
D
R
Y
T
A
V
A
M
P
M
L
Site 7
Y142
A
V
A
M
P
M
L
Y
N
T
R
Y
S
S
K
Site 8
T144
A
M
P
M
L
Y
N
T
R
Y
S
S
K
R
R
Site 9
Y146
P
M
L
Y
N
T
R
Y
S
S
K
R
R
V
T
Site 10
S147
M
L
Y
N
T
R
Y
S
S
K
R
R
V
T
V
Site 11
S148
L
Y
N
T
R
Y
S
S
K
R
R
V
T
V
M
Site 12
T225
R
R
R
K
R
V
N
T
K
R
S
S
R
A
F
Site 13
S228
K
R
V
N
T
K
R
S
S
R
A
F
R
A
H
Site 14
S229
R
V
N
T
K
R
S
S
R
A
F
R
A
H
L
Site 15
T254
P
E
D
M
K
L
C
T
V
I
M
K
S
N
G
Site 16
S262
V
I
M
K
S
N
G
S
F
P
V
N
R
R
R
Site 17
S285
E
L
E
M
E
M
L
S
S
T
S
P
P
E
R
Site 18
S286
L
E
M
E
M
L
S
S
T
S
P
P
E
R
T
Site 19
T287
E
M
E
M
L
S
S
T
S
P
P
E
R
T
R
Site 20
S288
M
E
M
L
S
S
T
S
P
P
E
R
T
R
Y
Site 21
Y295
S
P
P
E
R
T
R
Y
S
P
I
P
P
S
H
Site 22
S296
P
P
E
R
T
R
Y
S
P
I
P
P
S
H
H
Site 23
S301
R
Y
S
P
I
P
P
S
H
H
Q
L
T
L
P
Site 24
T306
P
P
S
H
H
Q
L
T
L
P
D
P
S
H
H
Site 25
S311
Q
L
T
L
P
D
P
S
H
H
G
L
H
S
T
Site 26
S317
P
S
H
H
G
L
H
S
T
P
D
S
P
A
K
Site 27
T318
S
H
H
G
L
H
S
T
P
D
S
P
A
K
P
Site 28
S321
G
L
H
S
T
P
D
S
P
A
K
P
E
K
N
Site 29
S354
P
N
G
K
T
R
T
S
L
K
T
M
S
R
R
Site 30
T357
K
T
R
T
S
L
K
T
M
S
R
R
K
L
S
Site 31
S359
R
T
S
L
K
T
M
S
R
R
K
L
S
Q
Q
Site 32
S364
T
M
S
R
R
K
L
S
Q
Q
K
E
K
K
A
Site 33
T428
V
N
P
I
I
Y
T
T
F
N
I
E
F
R
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation