PhosphoNET

           
Protein Info 
   
Short Name:  AKR1A1
Full Name:  Alcohol dehydrogenase [NADP+]
Alias:  AK1A1; Alcohol dehydrogenase; Alcohol dehydrogenase [NADP+]; Aldehyde reductase; Aldo-keto reductase family 1, member A1; Aldo-keto reductase family 1, member A1 (aldehyde reductase); ALDR1; ALR; DD3; Dihydrodiol dehydrogenase 3; EC 1.1.1.2
Type:  Oxidoreductase; Lipid Metabolism - glycerolipid; Carbohydrate Metabolism - glycolysis and gluconeogenesis; EC 1.1.1.2
Mass (Da):  36573
Number AA:  325
UniProt ID:  P14550
International Prot ID:  IPI00220271
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005829  GO:0016324  GO:0044424 Uniprot OncoNet
Molecular Function:  GO:0003824  GO:0004032  GO:0004033 PhosphoSite+ KinaseNET
Biological Process:  GO:0005975  GO:0005996  GO:0006006 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T21MPLIGLGTWKSEPGQ
Site 2S24IGLGTWKSEPGQVKA
Site 3Y50HIDCAAIYGNEPEIG
Site 4T78PREELFVTSKLWNTK
Site 5T98VEPALRKTLADLQLE
Site 6Y110QLEYLDLYLMHWPYA
Site 7Y135NADGTICYDSTHYKE
Site 8S166LGLSNFNSRQIDDIL
Site 9S174RQIDDILSVASVRPA
Site 10T208QARGLEVTAYSPLGS
Site 11Y210RGLEVTAYSPLGSSD
Site 12S211GLEVTAYSPLGSSDR
Site 13S215TAYSPLGSSDRAWRD
Site 14S216AYSPLGSSDRAWRDP
Site 15S244LAEKYGRSPAQILLR
Site 16S268IPKSITPSRILQNIK
Site 17T280NIKVFDFTFSPEEMK
Site 18S282KVFDFTFSPEEMKQL
Site 19Y319RDAGHPLYPFNDPY_
Site 20Y325LYPFNDPY_______
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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