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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
p47phox
Full Name:
Neutrophil cytosol factor 1
Alias:
47 kDa autosomal chronic granulomatous disease protein; 47 kDa neutrophil oxidase factor; Chronic granulomatous disease, autosomal 1; NADPH oxidase organizer 2; NCF1; NCF-1; NCF1A; NCF-47K; Neutrophil cytosolic factor 1; Neutrophil NADPH oxidase factor 1; NOXO2; P47 phox; P47-phox; SH3PXD1A
Type:
Oxidoreductase; EC 1.-.-.-
Mass (Da):
44683
Number AA:
390
UniProt ID:
P14598
International Prot ID:
IPI00788186
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0043020
GO:0005829
GO:0005625
Uniprot
OncoNet
Molecular Function:
GO:0005525
GO:0003924
GO:0017124
PhosphoSite+
KinaseNET
Biological Process:
GO:0007154
GO:0006968
GO:0045087
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S36
L
V
K
W
Q
D
L
S
E
K
V
V
Y
R
R
Site 2
Y41
D
L
S
E
K
V
V
Y
R
R
F
T
E
I
Y
Site 3
T45
K
V
V
Y
R
R
F
T
E
I
Y
E
F
H
K
Site 4
Y48
Y
R
R
F
T
E
I
Y
E
F
H
K
T
L
K
Site 5
T53
E
I
Y
E
F
H
K
T
L
K
E
M
F
P
I
Site 6
T93
A
A
E
N
R
Q
G
T
L
T
E
Y
C
S
T
Site 7
T95
E
N
R
Q
G
T
L
T
E
Y
C
S
T
L
M
Site 8
Y97
R
Q
G
T
L
T
E
Y
C
S
T
L
M
S
L
Site 9
T100
T
L
T
E
Y
C
S
T
L
M
S
L
P
T
K
Site 10
S103
E
Y
C
S
T
L
M
S
L
P
T
K
I
S
R
Site 11
T106
S
T
L
M
S
L
P
T
K
I
S
R
C
P
H
Site 12
S109
M
S
L
P
T
K
I
S
R
C
P
H
L
L
D
Site 13
T133
K
L
P
T
D
N
Q
T
K
K
P
E
T
Y
L
Site 14
T138
N
Q
T
K
K
P
E
T
Y
L
M
P
K
D
G
Site 15
Y139
Q
T
K
K
P
E
T
Y
L
M
P
K
D
G
K
Site 16
S147
L
M
P
K
D
G
K
S
T
A
T
D
I
T
G
Site 17
T153
K
S
T
A
T
D
I
T
G
P
I
I
L
Q
T
Site 18
Y167
T
Y
R
A
I
A
D
Y
E
K
T
S
G
S
E
Site 19
S173
D
Y
E
K
T
S
G
S
E
M
A
L
S
T
G
Site 20
S208
K
R
G
W
I
P
A
S
F
L
E
P
L
D
S
Site 21
S215
S
F
L
E
P
L
D
S
P
D
E
T
E
D
P
Site 22
T219
P
L
D
S
P
D
E
T
E
D
P
E
P
N
Y
Site 23
Y226
T
E
D
P
E
P
N
Y
A
G
E
P
Y
V
A
Site 24
Y231
P
N
Y
A
G
E
P
Y
V
A
I
K
A
Y
T
Site 25
Y237
P
Y
V
A
I
K
A
Y
T
A
V
E
G
D
E
Site 26
T272
V
I
R
K
D
D
V
T
G
Y
F
P
S
M
Y
Site 27
Y274
R
K
D
D
V
T
G
Y
F
P
S
M
Y
L
Q
Site 28
S277
D
V
T
G
Y
F
P
S
M
Y
L
Q
K
S
G
Site 29
Y279
T
G
Y
F
P
S
M
Y
L
Q
K
S
G
Q
D
Site 30
S283
P
S
M
Y
L
Q
K
S
G
Q
D
V
S
Q
A
Site 31
S288
Q
K
S
G
Q
D
V
S
Q
A
Q
R
Q
I
K
Site 32
S303
R
G
A
P
P
R
R
S
S
I
R
N
A
H
S
Site 33
S304
G
A
P
P
R
R
S
S
I
R
N
A
H
S
I
Site 34
S310
S
S
I
R
N
A
H
S
I
H
Q
R
S
R
K
Site 35
S315
A
H
S
I
H
Q
R
S
R
K
R
L
S
Q
D
Site 36
S320
Q
R
S
R
K
R
L
S
Q
D
A
Y
R
R
N
Site 37
Y324
K
R
L
S
Q
D
A
Y
R
R
N
S
V
R
F
Site 38
S328
Q
D
A
Y
R
R
N
S
V
R
F
L
Q
Q
R
Site 39
S345
Q
A
R
P
G
P
Q
S
P
G
S
P
L
E
E
Site 40
S348
P
G
P
Q
S
P
G
S
P
L
E
E
E
R
Q
Site 41
T356
P
L
E
E
E
R
Q
T
Q
R
S
K
P
Q
P
Site 42
S359
E
E
R
Q
T
Q
R
S
K
P
Q
P
A
V
P
Site 43
S370
P
A
V
P
P
R
P
S
A
D
L
I
L
N
R
Site 44
S379
D
L
I
L
N
R
C
S
E
S
T
K
R
K
L
Site 45
S381
I
L
N
R
C
S
E
S
T
K
R
K
L
A
S
Site 46
T382
L
N
R
C
S
E
S
T
K
R
K
L
A
S
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation