KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
HOXB3
Full Name:
Homeobox protein Hox-B3
Alias:
Homeobox protein Hox-2.7;Homeobox protein Hox-2G
Type:
Mass (Da):
44340
Number AA:
431
UniProt ID:
P14651
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S19
A
A
L
F
G
G
Y
S
S
Y
P
G
S
N
G
Site 2
S20
A
L
F
G
G
Y
S
S
Y
P
G
S
N
G
F
Site 3
Y21
L
F
G
G
Y
S
S
Y
P
G
S
N
G
F
G
Site 4
S24
G
Y
S
S
Y
P
G
S
N
G
F
G
F
D
V
Site 5
Y47
A
T
H
L
E
G
D
Y
Q
R
S
A
C
S
L
Site 6
S50
L
E
G
D
Y
Q
R
S
A
C
S
L
Q
S
L
Site 7
S53
D
Y
Q
R
S
A
C
S
L
Q
S
L
G
N
A
Site 8
S56
R
S
A
C
S
L
Q
S
L
G
N
A
A
P
H
Site 9
S72
K
S
K
E
L
N
G
S
C
M
R
P
G
L
A
Site 10
S84
G
L
A
P
E
P
L
S
A
P
P
G
S
P
P
Site 11
S89
P
L
S
A
P
P
G
S
P
P
P
S
A
A
P
Site 12
S93
P
P
G
S
P
P
P
S
A
A
P
T
S
A
T
Site 13
T97
P
P
P
S
A
A
P
T
S
A
T
S
N
S
S
Site 14
S98
P
P
S
A
A
P
T
S
A
T
S
N
S
S
N
Site 15
T100
S
A
A
P
T
S
A
T
S
N
S
S
N
G
G
Site 16
S101
A
A
P
T
S
A
T
S
N
S
S
N
G
G
G
Site 17
S103
P
T
S
A
T
S
N
S
S
N
G
G
G
P
S
Site 18
S104
T
S
A
T
S
N
S
S
N
G
G
G
P
S
K
Site 19
S110
S
S
N
G
G
G
P
S
K
S
G
P
P
K
C
Site 20
S112
N
G
G
G
P
S
K
S
G
P
P
K
C
G
P
Site 21
T121
P
P
K
C
G
P
G
T
N
S
T
L
T
K
Q
Site 22
T124
C
G
P
G
T
N
S
T
L
T
K
Q
I
F
P
Site 23
T139
W
M
K
E
S
R
Q
T
S
K
L
K
N
N
S
Site 24
S140
M
K
E
S
R
Q
T
S
K
L
K
N
N
S
P
Site 25
S146
T
S
K
L
K
N
N
S
P
G
T
A
E
G
C
Site 26
S165
G
G
G
G
G
G
G
S
G
G
S
G
G
G
G
Site 27
S168
G
G
G
G
S
G
G
S
G
G
G
G
G
G
G
Site 28
S181
G
G
G
G
G
D
K
S
P
P
G
S
A
A
S
Site 29
S185
G
D
K
S
P
P
G
S
A
A
S
K
R
A
R
Site 30
S188
S
P
P
G
S
A
A
S
K
R
A
R
T
A
Y
Site 31
T193
A
A
S
K
R
A
R
T
A
Y
T
S
A
Q
L
Site 32
Y195
S
K
R
A
R
T
A
Y
T
S
A
Q
L
V
E
Site 33
S197
R
A
R
T
A
Y
T
S
A
Q
L
V
E
L
E
Site 34
Y212
K
E
F
H
F
N
R
Y
L
C
R
P
R
R
V
Site 35
Y243
F
Q
N
R
R
M
K
Y
K
K
D
Q
K
A
K
Site 36
S254
Q
K
A
K
G
L
A
S
S
S
G
G
P
S
P
Site 37
S255
K
A
K
G
L
A
S
S
S
G
G
P
S
P
A
Site 38
S256
A
K
G
L
A
S
S
S
G
G
P
S
P
A
G
Site 39
S260
A
S
S
S
G
G
P
S
P
A
G
S
P
P
Q
Site 40
S264
G
G
P
S
P
A
G
S
P
P
Q
P
M
Q
S
Site 41
S271
S
P
P
Q
P
M
Q
S
T
A
G
F
M
N
A
Site 42
S281
G
F
M
N
A
L
H
S
M
T
P
S
Y
E
S
Site 43
T283
M
N
A
L
H
S
M
T
P
S
Y
E
S
P
S
Site 44
S285
A
L
H
S
M
T
P
S
Y
E
S
P
S
P
P
Site 45
Y286
L
H
S
M
T
P
S
Y
E
S
P
S
P
P
A
Site 46
S288
S
M
T
P
S
Y
E
S
P
S
P
P
A
F
G
Site 47
S290
T
P
S
Y
E
S
P
S
P
P
A
F
G
K
A
Site 48
Y302
G
K
A
H
Q
N
A
Y
A
L
P
S
N
Y
Q
Site 49
S306
Q
N
A
Y
A
L
P
S
N
Y
Q
P
P
L
K
Site 50
Y308
A
Y
A
L
P
S
N
Y
Q
P
P
L
K
G
C
Site 51
Y321
G
C
G
A
P
Q
K
Y
P
P
T
P
A
P
E
Site 52
T324
A
P
Q
K
Y
P
P
T
P
A
P
E
Y
E
P
Site 53
Y329
P
P
T
P
A
P
E
Y
E
P
H
V
L
Q
A
Site 54
Y341
L
Q
A
N
G
G
A
Y
G
T
P
T
M
Q
G
Site 55
T343
A
N
G
G
A
Y
G
T
P
T
M
Q
G
S
P
Site 56
T345
G
G
A
Y
G
T
P
T
M
Q
G
S
P
V
Y
Site 57
S349
G
T
P
T
M
Q
G
S
P
V
Y
V
G
G
G
Site 58
Y352
T
M
Q
G
S
P
V
Y
V
G
G
G
G
Y
A
Site 59
Y358
V
Y
V
G
G
G
G
Y
A
D
P
L
P
P
P
Site 60
S369
L
P
P
P
A
G
P
S
L
Y
G
L
N
H
L
Site 61
Y371
P
P
A
G
P
S
L
Y
G
L
N
H
L
S
H
Site 62
S377
L
Y
G
L
N
H
L
S
H
H
P
S
G
N
L
Site 63
S381
N
H
L
S
H
H
P
S
G
N
L
D
Y
N
G
Site 64
Y386
H
P
S
G
N
L
D
Y
N
G
A
P
P
M
A
Site 65
S395
G
A
P
P
M
A
P
S
Q
H
H
G
P
C
E
Site 66
T406
G
P
C
E
P
H
P
T
Y
T
D
L
S
S
H
Site 67
Y407
P
C
E
P
H
P
T
Y
T
D
L
S
S
H
H
Site 68
T408
C
E
P
H
P
T
Y
T
D
L
S
S
H
H
A
Site 69
S412
P
T
Y
T
D
L
S
S
H
H
A
P
P
P
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation