PhosphoNET

           
Protein Info 
   
Short Name:  TYR
Full Name:  Tyrosinase
Alias:  LB24-AB; monophenol monooxygenase; OCA1A; OCAIA; SK29-AB; tumor rejection antigen AB; TYRO; tyrosinase; tyrosinase (oculocutaneous albinism IA)
Type:  Amino Acid Metabolism - tyrosine; Oxidoreductase; Cofactor and Vitamin Metabolism - riboflavin; EC 1.14.18.1
Mass (Da):  60390
Number AA: 
UniProt ID:  P14679
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005798  GO:0016021  GO:0005764 Uniprot OncoNet
Molecular Function:  GO:0005507  GO:0004503  GO:0046982 PhosphoSite+ KinaseNET
Biological Process:  GO:0006726  GO:0006583  GO:0055114 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S16LLWSFQTSAGHFPRA
Site 2S26HFPRACVSSKNLMEK
Site 3S27FPRACVSSKNLMEKE
Site 4S44PPWSGDRSPCGQLSG
Site 5S50RSPCGQLSGRGSCQN
Site 6S54GQLSGRGSCQNILLS
Site 7S61SCQNILLSNAPLGPQ
Site 8T72LGPQFPFTGVDDRES
Site 9S79TGVDDRESWPSVFYN
Site 10T113GFWGPNCTERRLLVR
Site 11S127RRNIFDLSAPEKDKF
Site 12Y137EKDKFFAYLTLAKHT
Site 13Y149KHTISSDYVIPIGTY
Site 14T164GQMKNGSTPMFNDIN
Site 15S264PTNPNLLSPASFFSS
Site 16S271SPASFFSSWQIVCSR
Site 17S277SSWQIVCSRLEEYNS
Site 18Y282VCSRLEEYNSHQSLC
Site 19S284SRLEEYNSHQSLCNG
Site 20S287EEYNSHQSLCNGTPE
Site 21T292HQSLCNGTPEGPLRR
Site 22S307NPGNHDKSRTPRLPS
Site 23T309GNHDKSRTPRLPSSA
Site 24S314SRTPRLPSSADVEFC
Site 25S315RTPRLPSSADVEFCL
Site 26S323ADVEFCLSLTQYESG
Site 27Y327FCLSLTQYESGSMDK
Site 28S329LSLTQYESGSMDKAA
Site 29S339MDKAANFSFRNTLEG
Site 30T343ANFSFRNTLEGFASP
Site 31T352EGFASPLTGIADASQ
Site 32S358LTGIADASQSSMHNA
Site 33Y411HRPLQEVYPEANAPI
Site 34Y425IGHNRESYMVPFIPL
Site 35S441RNGDFFISSKDLGYD
Site 36Y447ISSKDLGYDYSYLQD
Site 37Y449SKDLGYDYSYLQDSD
Site 38S450KDLGYDYSYLQDSDP
Site 39Y451DLGYDYSYLQDSDPD
Site 40S455DYSYLQDSDPDSFQD
Site 41S459LQDSDPDSFQDYIKS
Site 42Y463DPDSFQDYIKSYLEQ
Site 43S466SFQDYIKSYLEQASR
Site 44Y467FQDYIKSYLEQASRI
Site 45S472KSYLEQASRIWSWLL
Site 46Y521LLMEKEDYHSLYQSH
Site 47S523MEKEDYHSLYQSHL_
Site 48S527DYHSLYQSHL_____
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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