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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MMP9
Full Name:
Matrix metalloproteinase-9
Alias:
92 kDa gelatinase; 92 kDa type IV collagenase precursor; CLG4B; Gelatinase B; gelatinase B gelatinase type IV collagenase; GELB; matrix metallopeptidase 9; MM09; MMP-9
Type:
Protease; EC 3.4.24.35
Mass (Da):
78427
Number AA:
707
UniProt ID:
P14780
International Prot ID:
IPI00027509
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005615
GO:0005578
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0005518
GO:0004222
PhosphoSite+
KinaseNET
Biological Process:
GO:0030574
GO:0030225
GO:0051549
Phosida
TranscriptoNet
STRING
Kinexus Products
Matrix metalloproteinase-9 pan-specific antibody AB-NN292-1#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NN292-1
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S26
A
A
P
R
Q
R
Q
S
T
L
V
L
F
P
G
Site 2
T27
A
P
R
Q
R
Q
S
T
L
V
L
F
P
G
D
Site 3
T40
G
D
L
R
T
N
L
T
D
R
Q
L
A
E
E
Site 4
Y48
D
R
Q
L
A
E
E
Y
L
Y
R
Y
G
Y
T
Site 5
Y50
Q
L
A
E
E
Y
L
Y
R
Y
G
Y
T
R
V
Site 6
Y54
E
Y
L
Y
R
Y
G
Y
T
R
V
A
E
M
R
Site 7
S64
V
A
E
M
R
G
E
S
K
S
L
G
P
A
L
Site 8
S66
E
M
R
G
E
S
K
S
L
G
P
A
L
L
L
Site 9
T83
K
Q
L
S
L
P
E
T
G
E
L
D
S
A
T
Site 10
S88
P
E
T
G
E
L
D
S
A
T
L
K
A
M
R
Site 11
T90
T
G
E
L
D
S
A
T
L
K
A
M
R
T
P
Site 12
T96
A
T
L
K
A
M
R
T
P
R
C
G
V
P
D
Site 13
T109
P
D
L
G
R
F
Q
T
F
E
G
D
L
K
W
Site 14
T155
W
S
A
V
T
P
L
T
F
T
R
V
Y
S
R
Site 15
Y160
P
L
T
F
T
R
V
Y
S
R
D
A
D
I
V
Site 16
Y179
V
A
E
H
G
D
G
Y
P
F
D
G
K
D
G
Site 17
S240
P
F
I
F
E
G
R
S
Y
S
A
C
T
T
D
Site 18
Y241
F
I
F
E
G
R
S
Y
S
A
C
T
T
D
G
Site 19
S242
I
F
E
G
R
S
Y
S
A
C
T
T
D
G
R
Site 20
T246
R
S
Y
S
A
C
T
T
D
G
R
S
D
G
L
Site 21
T264
S
T
T
A
N
Y
D
T
D
D
R
F
G
F
C
Site 22
S273
D
R
F
G
F
C
P
S
E
R
L
Y
T
Q
D
Site 23
Y277
F
C
P
S
E
R
L
Y
T
Q
D
G
N
A
D
Site 24
T278
C
P
S
E
R
L
Y
T
Q
D
G
N
A
D
G
Site 25
S300
I
F
Q
G
Q
S
Y
S
A
C
T
T
D
G
R
Site 26
T304
Q
S
Y
S
A
C
T
T
D
G
R
S
D
G
Y
Site 27
Y311
T
D
G
R
S
D
G
Y
R
W
C
A
T
T
A
Site 28
Y320
W
C
A
T
T
A
N
Y
D
R
D
K
L
F
G
Site 29
S335
F
C
P
T
R
A
D
S
T
V
M
G
G
N
S
Site 30
T336
C
P
T
R
A
D
S
T
V
M
G
G
N
S
A
Site 31
S359
T
F
L
G
K
E
Y
S
T
C
T
S
E
G
R
Site 32
S363
K
E
Y
S
T
C
T
S
E
G
R
G
D
G
R
Site 33
S377
R
L
W
C
A
T
T
S
N
F
D
S
D
K
K
Site 34
Y420
S
V
P
E
A
L
M
Y
P
M
Y
R
F
T
E
Site 35
Y423
E
A
L
M
Y
P
M
Y
R
F
T
E
G
P
P
Site 36
Y443
V
N
G
I
R
H
L
Y
G
P
R
P
E
P
E
Site 37
T455
E
P
E
P
R
P
P
T
T
T
T
P
Q
P
T
Site 38
T456
P
E
P
R
P
P
T
T
T
T
P
Q
P
T
A
Site 39
T457
E
P
R
P
P
T
T
T
T
P
Q
P
T
A
P
Site 40
T458
P
R
P
P
T
T
T
T
P
Q
P
T
A
P
P
Site 41
T466
P
Q
P
T
A
P
P
T
V
C
P
T
G
P
P
Site 42
T470
A
P
P
T
V
C
P
T
G
P
P
T
V
H
P
Site 43
T474
V
C
P
T
G
P
P
T
V
H
P
S
E
R
P
Site 44
S478
G
P
P
T
V
H
P
S
E
R
P
T
A
G
P
Site 45
T482
V
H
P
S
E
R
P
T
A
G
P
T
G
P
P
Site 46
T486
E
R
P
T
A
G
P
T
G
P
P
S
A
G
P
Site 47
S490
A
G
P
T
G
P
P
S
A
G
P
T
G
P
P
Site 48
T494
G
P
P
S
A
G
P
T
G
P
P
T
A
G
P
Site 49
T498
A
G
P
T
G
P
P
T
A
G
P
S
T
A
T
Site 50
T503
P
P
T
A
G
P
S
T
A
T
T
V
P
L
S
Site 51
Y532
A
E
I
G
N
Q
L
Y
L
F
K
D
G
K
Y
Site 52
Y539
Y
L
F
K
D
G
K
Y
W
R
F
S
E
G
R
Site 53
S543
D
G
K
Y
W
R
F
S
E
G
R
G
S
R
P
Site 54
S548
R
F
S
E
G
R
G
S
R
P
Q
G
P
F
L
Site 55
S569
A
L
P
R
K
L
D
S
V
F
E
E
P
L
S
Site 56
S619
Q
V
T
G
A
L
R
S
G
R
G
K
M
L
L
Site 57
S628
R
G
K
M
L
L
F
S
G
R
R
L
W
R
F
Site 58
S646
A
Q
M
V
D
P
R
S
A
S
E
V
D
R
M
Site 59
S648
M
V
D
P
R
S
A
S
E
V
D
R
M
F
P
Site 60
T661
F
P
G
V
P
L
D
T
H
D
V
F
Q
Y
R
Site 61
Y672
F
Q
Y
R
E
K
A
Y
F
C
Q
D
R
F
Y
Site 62
Y679
Y
F
C
Q
D
R
F
Y
W
R
V
S
S
R
S
Site 63
S683
D
R
F
Y
W
R
V
S
S
R
S
E
L
N
Q
Site 64
S684
R
F
Y
W
R
V
S
S
R
S
E
L
N
Q
V
Site 65
S686
Y
W
R
V
S
S
R
S
E
L
N
Q
V
D
Q
Site 66
Y696
N
Q
V
D
Q
V
G
Y
V
T
Y
D
I
L
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation