PhosphoNET

           
Protein Info 
   
Short Name:  HNRNPL
Full Name:  Heterogeneous nuclear ribonucleoprotein L
Alias:  HnRNP-L; HNRNPL (cDNA FLJ75895, highly similar to Homo sapiens heterogeneous nuclear ribonucleoprotein L (HNRPL), transcript variant 2, mRNA); HNRPL
Type:  RNA binding protein
Mass (Da):  64133
Number AA:  589
UniProt ID:  P14866
International Prot ID:  IPI00027834
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0030530  GO:0005654   Uniprot OncoNet
Molecular Function:  GO:0003723  GO:0000166  GO:0005515 PhosphoSite+ KinaseNET
Biological Process:  GO:0000398     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S29PDEQRRRSGAMVKMA
Site 2Y47GGGGGGRYYGGGSEG
Site 3Y48GGGGGRYYGGGSEGG
Site 4S52GRYYGGGSEGGRAPK
Site 5T63RAPKRLKTDNAGDQH
Site 6Y92GGGGGENYDDPHKTP
Site 7T98NYDDPHKTPASPVVH
Site 8S101DPHKTPASPVVHIRG
Site 9Y130QEFGPISYVVVMPKK
Site 10Y156GACNAVNYAADNQIY
Site 11Y173GHPAFVNYSTSQKIS
Site 12S174HPAFVNYSTSQKISR
Site 13S176AFVNYSTSQKISRPG
Site 14S180YSTSQKISRPGDSDD
Site 15S185KISRPGDSDDSRSVN
Site 16S188RPGDSDDSRSVNSVL
Site 17S190GDSDDSRSVNSVLLF
Site 18S240QAMVEFDSVQSAQRA
Site 19S250SAQRAKASLNGADIY
Site 20T262DIYSGCCTLKIEYAK
Site 21Y267CCTLKIEYAKPTRLN
Site 22Y285NDQDTWDYTNPNLSG
Site 23S291DYTNPNLSGQGDPGS
Site 24S298SGQGDPGSNPNKRQR
Site 25Y317LGDHPAEYGGPHGGY
Site 26Y324YGGPHGGYHSHYHDE
Site 27Y328HGGYHSHYHDEGYGP
Site 28Y333SHYHDEGYGPPPPHY
Site 29Y340YGPPPPHYEGRRMGP
Site 30S357GGHRRGPSRYGPQYG
Site 31Y359HRRGPSRYGPQYGHP
Site 32Y363PSRYGPQYGHPPPPP
Site 33Y375PPPPPPEYGPHADSP
Site 34S381EYGPHADSPVLMVYG
Site 35Y387DSPVLMVYGLDQSKM
Site 36S417EKVKFMKSKPGAAMV
Site 37S471SYGLEDGSCSYKDFS
Site 38S473GLEDGSCSYKDFSES
Site 39Y474LEDGSCSYKDFSESR
Site 40S478SCSYKDFSESRNNRF
Site 41S486ESRNNRFSTPEQAAK
Site 42T487SRNNRFSTPEQAAKN
Site 43S530ELGVKRPSSVKVFSG
Site 44S531LGVKRPSSVKVFSGK
Site 45S536PSSVKVFSGKSERSS
Site 46S539VKVFSGKSERSSSGL
Site 47S542FSGKSERSSSGLLEW
Site 48S543SGKSERSSSGLLEWE
Site 49S544GKSERSSSGLLEWES
Site 50S551SGLLEWESKSDALET
Site 51S553LLEWESKSDALETLG
Site 52T558SKSDALETLGFLNHY
Site 53Y565TLGFLNHYQMKNPNG
Site 54Y574MKNPNGPYPYTLKLC
Site 55Y576NPNGPYPYTLKLCFS
Site 56T577PNGPYPYTLKLCFST
Site 57S589FSTAQHAS_______
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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