KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
GABRA1
Full Name:
Gamma-aminobutyric acid receptor subunit alpha-1
Alias:
EJM; EJM5; GABA; GABA(A) receptor subunit alpha-1; Gamma-aminobutyric acid (GABA) A receptor, alpha 1; Gamma-aminobutyric-acid receptor alpha-1 subunit; GBRA1
Type:
Channel, ligand-gated
Mass (Da):
51802
Number AA:
456
UniProt ID:
P14867
International Prot ID:
IPI00295235
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030054
GO:0034707
GO:0005887
Uniprot
OncoNet
Molecular Function:
GO:0004890
GO:0005254
GO:0031404
PhosphoSite+
KinaseNET
Biological Process:
GO:0006821
GO:0007214
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T22
I
L
L
L
S
T
L
T
G
R
S
Y
G
Q
P
Site 2
Y26
S
T
L
T
G
R
S
Y
G
Q
P
S
L
Q
D
Site 3
Y53
L
D
R
L
L
D
G
Y
D
N
R
L
R
P
G
Site 4
Y156
T
E
D
G
T
L
L
Y
T
M
R
L
T
V
R
Site 5
Y237
V
Q
S
S
T
G
E
Y
V
V
M
T
T
H
F
Site 6
S278
S
F
W
L
N
R
E
S
V
P
A
R
T
V
F
Site 7
S299
T
M
T
T
L
S
I
S
A
R
N
S
L
P
K
Site 8
Y336
I
E
F
A
T
V
N
Y
F
T
K
R
G
Y
A
Site 9
Y342
N
Y
F
T
K
R
G
Y
A
W
D
G
K
S
V
Site 10
S348
G
Y
A
W
D
G
K
S
V
V
P
E
K
P
K
Site 11
Y368
L
I
K
K
N
N
T
Y
A
P
T
A
T
S
Y
Site 12
S374
T
Y
A
P
T
A
T
S
Y
T
P
N
L
A
R
Site 13
Y375
Y
A
P
T
A
T
S
Y
T
P
N
L
A
R
G
Site 14
T376
A
P
T
A
T
S
Y
T
P
N
L
A
R
G
D
Site 15
S392
G
L
A
T
I
A
K
S
A
T
I
E
P
K
E
Site 16
T394
A
T
I
A
K
S
A
T
I
E
P
K
E
V
K
Site 17
T404
P
K
E
V
K
P
E
T
K
P
P
E
P
K
K
Site 18
T412
K
P
P
E
P
K
K
T
F
N
S
V
S
K
I
Site 19
S415
E
P
K
K
T
F
N
S
V
S
K
I
D
R
L
Site 20
S417
K
K
T
F
N
S
V
S
K
I
D
R
L
S
R
Site 21
Y442
N
L
V
Y
W
A
T
Y
L
N
R
E
P
Q
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation