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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Ets-1
Full Name:
Protein C-ets-1
Alias:
Avian erythroblastosis virus E26 (v-ets) oncogene-1; C-ets-1 protein; Ets protein; Ets1; ETS-1; ETS1A; EWSR2; FLJ10768; P54; V-ets erythroblastosis virus E26 oncogene 1
Type:
Transcription protein
Mass (Da):
50408
Number AA:
441
UniProt ID:
P14921
International Prot ID:
IPI00028127
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003702
GO:0005515
GO:0043565
PhosphoSite+
KinaseNET
Biological Process:
GO:0030578
GO:0048870
GO:0006955
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S26
V
D
L
E
L
F
P
S
P
D
M
E
C
A
D
Site 2
T38
C
A
D
V
P
L
L
T
P
S
S
K
E
M
M
Site 3
S41
V
P
L
L
T
P
S
S
K
E
M
M
S
Q
A
Site 4
S46
P
S
S
K
E
M
M
S
Q
A
L
K
A
T
F
Site 5
T52
M
S
Q
A
L
K
A
T
F
S
G
F
T
K
E
Site 6
S54
Q
A
L
K
A
T
F
S
G
F
T
K
E
Q
Q
Site 7
Y140
Q
K
E
D
V
K
P
Y
Q
V
N
G
V
N
P
Site 8
Y149
V
N
G
V
N
P
A
Y
P
E
S
R
Y
T
S
Site 9
S152
V
N
P
A
Y
P
E
S
R
Y
T
S
D
Y
F
Site 10
Y154
P
A
Y
P
E
S
R
Y
T
S
D
Y
F
I
S
Site 11
T155
A
Y
P
E
S
R
Y
T
S
D
Y
F
I
S
Y
Site 12
S156
Y
P
E
S
R
Y
T
S
D
Y
F
I
S
Y
G
Site 13
Y158
E
S
R
Y
T
S
D
Y
F
I
S
Y
G
I
E
Site 14
S173
H
A
Q
C
V
P
P
S
E
F
S
E
P
S
F
Site 15
S176
C
V
P
P
S
E
F
S
E
P
S
F
I
T
E
Site 16
S179
P
S
E
F
S
E
P
S
F
I
T
E
S
Y
Q
Site 17
Y185
P
S
F
I
T
E
S
Y
Q
T
L
H
P
I
S
Site 18
T187
F
I
T
E
S
Y
Q
T
L
H
P
I
S
S
E
Site 19
S192
Y
Q
T
L
H
P
I
S
S
E
E
L
L
S
L
Site 20
S193
Q
T
L
H
P
I
S
S
E
E
L
L
S
L
K
Site 21
S198
I
S
S
E
E
L
L
S
L
K
Y
E
N
D
Y
Site 22
Y201
E
E
L
L
S
L
K
Y
E
N
D
Y
P
S
V
Site 23
Y205
S
L
K
Y
E
N
D
Y
P
S
V
I
L
R
D
Site 24
S207
K
Y
E
N
D
Y
P
S
V
I
L
R
D
P
L
Site 25
T216
I
L
R
D
P
L
Q
T
D
T
L
Q
N
D
Y
Site 26
T218
R
D
P
L
Q
T
D
T
L
Q
N
D
Y
F
A
Site 27
Y223
T
D
T
L
Q
N
D
Y
F
A
I
K
Q
E
V
Site 28
T232
A
I
K
Q
E
V
V
T
P
D
N
M
C
M
G
Site 29
T241
D
N
M
C
M
G
R
T
S
R
G
K
L
G
G
Site 30
S242
N
M
C
M
G
R
T
S
R
G
K
L
G
G
Q
Site 31
S251
G
K
L
G
G
Q
D
S
F
E
S
I
E
S
Y
Site 32
S254
G
G
Q
D
S
F
E
S
I
E
S
Y
D
S
C
Site 33
S257
D
S
F
E
S
I
E
S
Y
D
S
C
D
R
L
Site 34
Y258
S
F
E
S
I
E
S
Y
D
S
C
D
R
L
T
Site 35
S260
E
S
I
E
S
Y
D
S
C
D
R
L
T
Q
S
Site 36
T265
Y
D
S
C
D
R
L
T
Q
S
W
S
S
Q
S
Site 37
S267
S
C
D
R
L
T
Q
S
W
S
S
Q
S
S
F
Site 38
S269
D
R
L
T
Q
S
W
S
S
Q
S
S
F
N
S
Site 39
S270
R
L
T
Q
S
W
S
S
Q
S
S
F
N
S
L
Site 40
S272
T
Q
S
W
S
S
Q
S
S
F
N
S
L
Q
R
Site 41
S273
Q
S
W
S
S
Q
S
S
F
N
S
L
Q
R
V
Site 42
S276
S
S
Q
S
S
F
N
S
L
Q
R
V
P
S
Y
Site 43
S282
N
S
L
Q
R
V
P
S
Y
D
S
F
D
S
E
Site 44
Y283
S
L
Q
R
V
P
S
Y
D
S
F
D
S
E
D
Site 45
S285
Q
R
V
P
S
Y
D
S
F
D
S
E
D
Y
P
Site 46
S288
P
S
Y
D
S
F
D
S
E
D
Y
P
A
A
L
Site 47
Y291
D
S
F
D
S
E
D
Y
P
A
A
L
P
N
H
Site 48
T303
P
N
H
K
P
K
G
T
F
K
D
Y
V
R
D
Site 49
Y307
P
K
G
T
F
K
D
Y
V
R
D
R
A
D
L
Site 50
S349
L
E
L
L
T
D
K
S
C
Q
S
F
I
S
W
Site 51
S352
L
T
D
K
S
C
Q
S
F
I
S
W
T
G
D
Site 52
S366
D
G
W
E
F
K
L
S
D
P
D
E
V
A
R
Site 53
Y386
K
N
K
P
K
M
N
Y
E
K
L
S
R
G
L
Site 54
Y396
L
S
R
G
L
R
Y
Y
Y
D
K
N
I
I
H
Site 55
Y397
S
R
G
L
R
Y
Y
Y
D
K
N
I
I
H
K
Site 56
T405
D
K
N
I
I
H
K
T
A
G
K
R
Y
V
Y
Site 57
Y410
H
K
T
A
G
K
R
Y
V
Y
R
F
V
C
D
Site 58
Y412
T
A
G
K
R
Y
V
Y
R
F
V
C
D
L
Q
Site 59
S420
R
F
V
C
D
L
Q
S
L
L
G
Y
T
P
E
Site 60
Y424
D
L
Q
S
L
L
G
Y
T
P
E
E
L
H
A
Site 61
T425
L
Q
S
L
L
G
Y
T
P
E
E
L
H
A
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation