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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Ets-2
Full Name:
Protein C-ets-2
Alias:
C-ets-2 protein; ETS2; v-ets erythroblastosis virus E26 oncogene 2
Type:
Transcription protein
Mass (Da):
53001
Number AA:
469
UniProt ID:
P15036
International Prot ID:
IPI00009756
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0045893
GO:0001501
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
Q
V
A
P
V
A
N
S
Y
R
G
T
L
K
R
Site 2
T22
V
A
N
S
Y
R
G
T
L
K
R
Q
P
A
F
Site 3
T31
K
R
Q
P
A
F
D
T
F
D
G
S
L
F
A
Site 4
T48
P
S
L
N
E
E
Q
T
L
Q
E
V
P
T
G
Site 5
T54
Q
T
L
Q
E
V
P
T
G
L
D
S
I
S
H
Site 6
S58
E
V
P
T
G
L
D
S
I
S
H
D
S
A
N
Site 7
S60
P
T
G
L
D
S
I
S
H
D
S
A
N
C
E
Site 8
S63
L
D
S
I
S
H
D
S
A
N
C
E
L
P
L
Site 9
T72
N
C
E
L
P
L
L
T
P
C
S
K
A
V
M
Site 10
T86
M
S
Q
A
L
K
A
T
F
S
G
F
K
K
E
Site 11
S88
Q
A
L
K
A
T
F
S
G
F
K
K
E
Q
R
Site 12
Y178
Q
E
K
T
E
D
Q
Y
E
E
N
S
H
L
T
Site 13
S182
E
D
Q
Y
E
E
N
S
H
L
T
S
V
P
H
Site 14
S186
E
E
N
S
H
L
T
S
V
P
H
W
I
N
S
Site 15
Y205
F
G
T
E
Q
A
P
Y
G
M
Q
T
Q
N
Y
Site 16
Y212
Y
G
M
Q
T
Q
N
Y
P
K
G
G
L
L
D
Site 17
S220
P
K
G
G
L
L
D
S
M
C
P
A
S
T
P
Site 18
T226
D
S
M
C
P
A
S
T
P
S
V
L
S
S
E
Site 19
S228
M
C
P
A
S
T
P
S
V
L
S
S
E
Q
E
Site 20
S231
A
S
T
P
S
V
L
S
S
E
Q
E
F
Q
M
Site 21
S232
S
T
P
S
V
L
S
S
E
Q
E
F
Q
M
F
Site 22
S242
E
F
Q
M
F
P
K
S
R
L
S
S
V
S
V
Site 23
S246
F
P
K
S
R
L
S
S
V
S
V
T
Y
C
S
Site 24
S248
K
S
R
L
S
S
V
S
V
T
Y
C
S
V
S
Site 25
T250
R
L
S
S
V
S
V
T
Y
C
S
V
S
Q
D
Site 26
S253
S
V
S
V
T
Y
C
S
V
S
Q
D
F
P
G
Site 27
S255
S
V
T
Y
C
S
V
S
Q
D
F
P
G
S
N
Site 28
S261
V
S
Q
D
F
P
G
S
N
L
N
L
L
T
N
Site 29
T267
G
S
N
L
N
L
L
T
N
N
S
G
T
P
K
Site 30
S270
L
N
L
L
T
N
N
S
G
T
P
K
D
H
D
Site 31
T272
L
L
T
N
N
S
G
T
P
K
D
H
D
S
P
Site 32
S278
G
T
P
K
D
H
D
S
P
E
N
G
A
D
S
Site 33
S285
S
P
E
N
G
A
D
S
F
E
S
S
D
S
L
Site 34
S288
N
G
A
D
S
F
E
S
S
D
S
L
L
Q
S
Site 35
S289
G
A
D
S
F
E
S
S
D
S
L
L
Q
S
W
Site 36
S291
D
S
F
E
S
S
D
S
L
L
Q
S
W
N
S
Site 37
S295
S
S
D
S
L
L
Q
S
W
N
S
Q
S
S
L
Site 38
S298
S
L
L
Q
S
W
N
S
Q
S
S
L
L
D
V
Site 39
S301
Q
S
W
N
S
Q
S
S
L
L
D
V
Q
R
V
Site 40
S310
L
D
V
Q
R
V
P
S
F
E
S
F
E
D
D
Site 41
S313
Q
R
V
P
S
F
E
S
F
E
D
D
C
S
Q
Site 42
S319
E
S
F
E
D
D
C
S
Q
S
L
C
L
N
K
Site 43
S321
F
E
D
D
C
S
Q
S
L
C
L
N
K
P
T
Site 44
Y334
P
T
M
S
F
K
D
Y
I
Q
E
R
S
D
P
Site 45
S339
K
D
Y
I
Q
E
R
S
D
P
V
E
Q
G
K
Site 46
S377
L
E
L
L
S
D
K
S
C
Q
S
F
I
S
W
Site 47
S380
L
S
D
K
S
C
Q
S
F
I
S
W
T
G
D
Site 48
Y414
K
N
K
P
K
M
N
Y
E
K
L
S
R
G
L
Site 49
Y424
L
S
R
G
L
R
Y
Y
Y
D
K
N
I
I
H
Site 50
Y425
S
R
G
L
R
Y
Y
Y
D
K
N
I
I
H
K
Site 51
Y438
H
K
T
S
G
K
R
Y
V
Y
R
F
V
C
D
Site 52
Y440
T
S
G
K
R
Y
V
Y
R
F
V
C
D
L
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation