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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CPA3
Full Name:
Mast cell carboxypeptidase A
Alias:
Carboxypeptidase A3
Type:
Mass (Da):
48700
Number AA:
417
UniProt ID:
P15088
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S71
M
M
V
D
F
R
V
S
E
K
E
S
Q
A
I
Site 2
S75
F
R
V
S
E
K
E
S
Q
A
I
Q
S
A
L
Site 3
Y116
D
I
P
G
R
H
S
Y
A
K
Y
N
N
W
E
Site 4
Y119
G
R
H
S
Y
A
K
Y
N
N
W
E
K
I
V
Site 5
Y136
T
E
K
M
M
D
K
Y
P
E
M
V
S
R
I
Site 6
S147
V
S
R
I
K
I
G
S
T
V
E
D
N
P
L
Site 7
T148
S
R
I
K
I
G
S
T
V
E
D
N
P
L
Y
Site 8
Y155
T
V
E
D
N
P
L
Y
V
L
K
I
G
E
K
Site 9
T196
F
V
Y
Q
A
T
K
T
Y
G
R
N
K
I
M
Site 10
T204
Y
G
R
N
K
I
M
T
K
L
L
D
R
M
N
Site 11
S257
L
N
R
N
F
N
A
S
W
N
S
I
P
N
T
Site 12
S260
N
F
N
A
S
W
N
S
I
P
N
T
N
D
P
Site 13
T264
S
W
N
S
I
P
N
T
N
D
P
C
A
D
N
Site 14
Y272
N
D
P
C
A
D
N
Y
R
G
S
A
P
E
S
Site 15
S275
C
A
D
N
Y
R
G
S
A
P
E
S
E
K
E
Site 16
S279
Y
R
G
S
A
P
E
S
E
K
E
T
K
A
V
Site 17
T283
A
P
E
S
E
K
E
T
K
A
V
T
N
F
I
Site 18
Y300
H
L
N
E
I
K
V
Y
I
T
F
H
S
Y
S
Site 19
Y314
S
Q
M
L
L
F
P
Y
G
Y
T
S
K
L
P
Site 20
Y316
M
L
L
F
P
Y
G
Y
T
S
K
L
P
P
N
Site 21
S318
L
F
P
Y
G
Y
T
S
K
L
P
P
N
H
E
Site 22
T335
A
K
V
A
K
I
G
T
D
V
L
S
T
R
Y
Site 23
S339
K
I
G
T
D
V
L
S
T
R
Y
E
T
R
Y
Site 24
T344
V
L
S
T
R
Y
E
T
R
Y
I
Y
G
P
I
Site 25
Y346
S
T
R
Y
E
T
R
Y
I
Y
G
P
I
E
S
Site 26
Y348
R
Y
E
T
R
Y
I
Y
G
P
I
E
S
T
I
Site 27
Y356
G
P
I
E
S
T
I
Y
P
I
S
G
S
S
L
Site 28
S359
E
S
T
I
Y
P
I
S
G
S
S
L
D
W
A
Site 29
S361
T
I
Y
P
I
S
G
S
S
L
D
W
A
Y
D
Site 30
Y367
G
S
S
L
D
W
A
Y
D
L
G
I
K
H
T
Site 31
T374
Y
D
L
G
I
K
H
T
F
A
F
E
L
R
D
Site 32
S392
F
G
F
L
L
P
E
S
R
I
K
P
T
C
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation