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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GLUL
Full Name:
Glutamine synthetase
Alias:
GLNA; GLNS; Glutamate-ammonia ligase; GS; PIG43
Type:
Ligase; EC 6.3.1.2; Energy Metabolism - nitrogen; Amino Acid Metabolism - alanine, aspartate and glutamate; Amino Acid Metabolism - arginine and proline
Mass (Da):
42064
Number AA:
373
UniProt ID:
P15104
International Prot ID:
IPI00010130
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0005829
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0004356
GO:0042802
PhosphoSite+
KinaseNET
Biological Process:
GO:0008283
GO:0006542
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y17
N
K
G
I
K
Q
V
Y
M
S
L
P
Q
G
E
Site 2
S19
G
I
K
Q
V
Y
M
S
L
P
Q
G
E
K
V
Site 3
Y30
G
E
K
V
Q
A
M
Y
I
W
I
D
G
T
G
Site 4
T44
G
E
G
L
R
C
K
T
R
T
L
D
S
E
P
Site 5
T46
G
L
R
C
K
T
R
T
L
D
S
E
P
K
C
Site 6
S49
C
K
T
R
T
L
D
S
E
P
K
C
V
E
E
Site 7
S65
P
E
W
N
F
D
G
S
S
T
L
Q
S
E
G
Site 8
S66
E
W
N
F
D
G
S
S
T
L
Q
S
E
G
S
Site 9
T67
W
N
F
D
G
S
S
T
L
Q
S
E
G
S
N
Site 10
S70
D
G
S
S
T
L
Q
S
E
G
S
N
S
D
M
Site 11
S73
S
T
L
Q
S
E
G
S
N
S
D
M
Y
L
V
Site 12
S75
L
Q
S
E
G
S
N
S
D
M
Y
L
V
P
A
Site 13
Y104
V
L
C
E
V
F
K
Y
N
R
R
P
A
E
T
Site 14
T111
Y
N
R
R
P
A
E
T
N
L
R
H
T
C
K
Site 15
Y137
W
F
G
M
E
Q
E
Y
T
L
M
G
T
D
G
Site 16
T138
F
G
M
E
Q
E
Y
T
L
M
G
T
D
G
H
Site 17
Y161
F
P
G
P
Q
G
P
Y
Y
C
G
V
G
A
D
Site 18
Y162
P
G
P
Q
G
P
Y
Y
C
G
V
G
A
D
R
Site 19
Y171
G
V
G
A
D
R
A
Y
G
R
D
I
V
E
A
Site 20
Y180
R
D
I
V
E
A
H
Y
R
A
C
L
Y
A
G
Site 21
Y185
A
H
Y
R
A
C
L
Y
A
G
V
K
I
A
G
Site 22
T237
E
D
F
G
V
I
A
T
F
D
P
K
P
I
P
Site 23
Y269
R
E
E
N
G
L
K
Y
I
E
E
A
I
E
K
Site 24
S278
E
E
A
I
E
K
L
S
K
R
H
Q
Y
H
I
Site 25
Y283
K
L
S
K
R
H
Q
Y
H
I
R
A
Y
D
P
Site 26
Y288
H
Q
Y
H
I
R
A
Y
D
P
K
G
G
L
D
Site 27
T301
L
D
N
A
R
R
L
T
G
F
H
E
T
S
N
Site 28
S320
S
A
G
V
A
N
R
S
A
S
I
R
I
P
R
Site 29
S322
G
V
A
N
R
S
A
S
I
R
I
P
R
T
V
Site 30
T328
A
S
I
R
I
P
R
T
V
G
Q
E
K
K
G
Site 31
Y336
V
G
Q
E
K
K
G
Y
F
E
D
R
R
P
S
Site 32
S343
Y
F
E
D
R
R
P
S
A
N
C
D
P
F
S
Site 33
Y371
T
G
D
E
P
F
Q
Y
K
N
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation