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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CPN1
Full Name:
Carboxypeptidase N catalytic chain
Alias:
Anaphylatoxin inactivator;Arginine carboxypeptidase;Carboxypeptidase N polypeptide 1;Carboxypeptidase N small subunit;Kininase-1;Lysine carboxypeptidase;Plasma carboxypeptidase B;Serum carboxypeptidase N
Type:
Mass (Da):
52286
Number AA:
458
UniProt ID:
P15169
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T22
F
K
L
V
A
P
V
T
F
R
H
H
R
Y
D
Site 2
Y36
D
D
L
V
R
T
L
Y
K
V
Q
N
E
C
P
Site 3
Y49
C
P
G
I
T
R
V
Y
S
I
G
R
S
V
E
Site 4
S50
P
G
I
T
R
V
Y
S
I
G
R
S
V
E
G
Site 5
S54
R
V
Y
S
I
G
R
S
V
E
G
R
H
L
Y
Site 6
Y61
S
V
E
G
R
H
L
Y
V
L
E
F
S
D
H
Site 7
S66
H
L
Y
V
L
E
F
S
D
H
P
G
I
H
E
Site 8
Y81
P
L
E
P
E
V
K
Y
V
G
N
M
H
G
N
Site 9
S128
T
R
I
H
I
L
P
S
M
N
P
D
G
Y
E
Site 10
Y134
P
S
M
N
P
D
G
Y
E
V
A
A
A
Q
G
Site 11
Y147
Q
G
P
N
K
P
G
Y
L
V
G
R
N
N
A
Site 12
Y169
N
F
P
D
L
N
T
Y
I
Y
Y
N
E
K
Y
Site 13
Y171
P
D
L
N
T
Y
I
Y
Y
N
E
K
Y
G
G
Site 14
Y172
D
L
N
T
Y
I
Y
Y
N
E
K
Y
G
G
P
Site 15
Y176
Y
I
Y
Y
N
E
K
Y
G
G
P
N
H
H
L
Site 16
S191
P
L
P
D
N
W
K
S
Q
V
E
P
E
T
R
Site 17
Y224
G
G
A
V
V
A
N
Y
P
Y
D
K
S
F
E
Site 18
Y226
A
V
V
A
N
Y
P
Y
D
K
S
F
E
H
R
Site 19
S229
A
N
Y
P
Y
D
K
S
F
E
H
R
V
R
G
Site 20
T240
R
V
R
G
V
R
R
T
A
S
T
P
T
P
D
Site 21
S242
R
G
V
R
R
T
A
S
T
P
T
P
D
D
K
Site 22
T243
G
V
R
R
T
A
S
T
P
T
P
D
D
K
L
Site 23
T245
R
R
T
A
S
T
P
T
P
D
D
K
L
F
Q
Site 24
S284
D
G
I
T
N
G
A
S
W
Y
S
L
S
K
G
Site 25
S287
T
N
G
A
S
W
Y
S
L
S
K
G
M
Q
D
Site 26
S289
G
A
S
W
Y
S
L
S
K
G
M
Q
D
F
N
Site 27
T306
H
T
N
C
F
E
I
T
L
E
L
S
C
D
K
Site 28
S310
F
E
I
T
L
E
L
S
C
D
K
F
P
P
E
Site 29
Y351
G
M
V
L
D
E
N
Y
N
N
L
A
N
A
V
Site 30
T369
S
G
I
N
H
D
V
T
S
G
D
H
G
D
Y
Site 31
Y376
T
S
G
D
H
G
D
Y
F
R
L
L
L
P
G
Site 32
T398
A
P
G
Y
D
P
E
T
V
T
V
T
V
G
P
Site 33
T400
G
Y
D
P
E
T
V
T
V
T
V
G
P
A
E
Site 34
T402
D
P
E
T
V
T
V
T
V
G
P
A
E
P
T
Site 35
S423
K
R
S
I
P
Q
V
S
P
V
R
R
A
P
S
Site 36
S430
S
P
V
R
R
A
P
S
R
R
H
G
V
R
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation